The Antagonistic Action of Abscisic Acid and Cytokinin Signaling Mediates Drought Stress Response in Arabidopsis

Huang, Xiaozhen; Hou, Lingyan; Meng, Jingjing; You, Huiwen; Li, Zhen; Gong, Zhizhong; Yang, Shuhua; Shi, Yiting

doi:10.1016/j.molp.2018.05.001

Cited by 204 publications

(148 citation statements)

References 65 publications

(79 reference statements)

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“…Plants react to water-limiting conditions by reducing their cytokinin levels, mainly through the modulation of cytokinin metabolism—as shown ( inter alia ) in Arabidopsis , creeping bentgrass, soybean, tobacco, and sunflower [88,89,90,91,92,93]—and/or the regulation of cytokinin receptors’ expression [94,95]. However, other mechanisms, including activation of the negative regulators of cytokinin signalling AHP6 and ARR5 also probably participate in this process [94,96,97]. Appropriate modulation of cytokinin metabolism and signalling has been known to improve drought and salt tolerance for many years [92,95,98,99], and at least five mechanisms may contribute to cytokinin-mediated enhancement of tolerance of water deficiency.…”

Section: Cytokinin Roles In Drought and Salinity Tolerancementioning

confidence: 99%

“…However, elucidation of the molecular mechanism involved in this interaction has begun only recently. Experiments with a series of cytokinin and abscisic acid signalling mutants have demonstrated that cytokinin and abscisic acid interact directly through their signalling components, as plants constitutively expressing HA-Flag-ARR5 and arr5 loss-of-function mutants respectively showed increased and attenuated sensitivity to abscisic acid treatment [97]. ARR5 stability is promoted by phosphorylation catalysed by SnRK2 protein kinases that are key components of the abscisic acid signalling pathway.…”

Section: Cytokinin Roles In Drought and Salinity Tolerancementioning

confidence: 99%

“…ARR5 stability is promoted by phosphorylation catalysed by SnRK2 protein kinases that are key components of the abscisic acid signalling pathway. In contrast, type-B ARR1, 11, and 12 interact with these SnRK2s and repress their kinase activity, and the abscisic acid hypersensitivity of the triple mutant arr1,11,12 can be completely rescued by mutation of SnRK2s [97]. Interestingly, the same authors found that expression of ARR1ΔDDK (a constitutively activated form of ARR1), but not constitutive expression of ARR1-Myc , was associated with slight insensitivity to abscisic acid, suggesting that the modulation of ARR1’s phosphorylation status by cytokinin signalling may also be important.…”

Section: Cytokinin Roles In Drought and Salinity Tolerancementioning

confidence: 99%

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Cytokinin at the Crossroads of Abiotic Stress Signalling Pathways

Pavlů

Novák

Koukalová

et al. 2018

IJMS

126

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Cytokinin is a multifaceted plant hormone that plays major roles not only in diverse plant growth and development processes, but also stress responses. We summarize knowledge of the roles of its metabolism, transport, and signalling in responses to changes in levels of both macronutrients (nitrogen, phosphorus, potassium, sulphur) and micronutrients (boron, iron, silicon, selenium). We comment on cytokinin’s effects on plants’ xenobiotic resistance, and its interactions with light, temperature, drought, and salinity signals. Further, we have compiled a list of abiotic stress-related genes and demonstrate that their expression patterns overlap with those of cytokinin metabolism and signalling genes.

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Section: Cytokinin Roles In Drought and Salinity Tolerancementioning

confidence: 99%

Section: Cytokinin Roles In Drought and Salinity Tolerancementioning

confidence: 99%

Section: Cytokinin Roles In Drought and Salinity Tolerancementioning

confidence: 99%

See 1 more Smart Citation

Cytokinin at the Crossroads of Abiotic Stress Signalling Pathways

Pavlů

Novák

Koukalová

et al. 2018

IJMS

126

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“…During the regulation of auxin synthesis, EIN3 interacts with the C-terminus of ARR1 and thereby increases ARR1 activity (Yan et al, 2017). As part of the crosstalk between CK and abscisic acid, ARR1, ARR11 and ARR12 directly interact with SUCROSE NON-FERMENTING-1 (SNF1)- RELATED PROTEIN KINASE2 (SnRK2) kinases and thereby inhibit their function prior to drought stress (Huang et al, 2018). Future experiments might resolve whether and how type-B ARRs interact with each other or with other proteins during photoperiod stress.…”

Section: Discussionmentioning

confidence: 99%

Root-derived trans-zeatin cytokinin protects Arabidopsis plants against photoperiod stress

Frank

Cortleven

Schmülling

2020

Preprint

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Running title: Protective role of root-borne cytokinin 1 2 Root-derived trans-zeatin cytokinin protects Arabidopsis plants against photoperiod 3 stress 4 5 ABSTRACT 27 Recently, a novel type of abiotic stress caused by a prolongation of the light period -coined 28 photoperiod stress -has been described in Arabidopsis. During the night after the 29 prolongation of the light period, stress and cell death marker genes are induced. The next day, 30 strongly stressed plants display a reduced photosynthetic efficiency and leaf cells eventually 31 enter programmed cell death. The phytohormone cytokinin (CK) acts as a negative regulator of 32 this photoperiod stress syndrome. In this study, we show that Arabidopsis wild-type plants 33 increase the CK concentration in response to photoperiod stress. Analysis of cytokinin 34 synthesis and transport mutants revealed that root-derived trans-zeatin (tZ)-type CKs protect 35 against photoperiod stress. The CK signaling proteins ARABIDOPSIS HISTIDINE 36 PHOSPHOTRANSFER PROTEIN 2 (AHP2), AHP3 and AHP5 and transcription factors 37 ARABIDOPSIS RESPONSE REGULATOR 2 (ARR2), ARR10 and ARR12 are required for the 38 protective activity of CK. Analysis of higher order B-type arr mutants suggested that a complex 39 regulatory circuit exists in which the loss of ARR10 or ARR12 can rescue the arr2 phenotype. 40 Together the results revealed the role of root-derived CK acting in the shoot through the two-41 component signaling system to protect from the negative consequences of strong photoperiod 42 stress. 43 44 45

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“…ABA-signaling might regulate SL biosynthesis [190]. The antagonistic action of ABA and Cytokinin signaling mediates drought stress response in Arabidopsis [191]. Karrikin-signaling pathway seems to be upstream of ABA-signaling pathway and karrikin-mediates changes in ABA-related gene expression [192].…”

Section: Other Aspect Of Aba Signalingmentioning

confidence: 99%

Integration of Abscisic Acid Signaling with Other Signaling Pathways in Plant Stress Responses and Development

Kumar¹,

Kesawat²,

Ali³

et al. 2019

Preprint

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Plants are immobile, and, to overcome harsh environmental conditions, such as drought, salt, and cold, they have evolved complex signaling pathways. Abscisic acid (ABA), an isoprenoid phytohormone, is a critical signaling mediator that regulates diverse biological processes in various organisms. Significant progress has been made in the determination and characterization of key ABA-mediated molecular factors involved in different stress responses, including stomatal closure and developmental processes, such as seed germination and bud dormancy. Since ABA-signaling is a complex signaling network that integrates with other signaling pathways, the dissection of its intricate regulatory network is necessary to understand the function of essential regulatory genes involved in ABA signaling. In the present review, we focus on two aspects of ABA signaling. First, the perception of the stress signal (abiotic and biotic) and the response network of ABA-signaling components that transduce the signal to the downstream pathway to respond to stress tolerance, regulation of stomata, and ABA signaling component ubiquitination. Second, ABA-signaling in plant development processes, such as lateral root growth regulation, seed germination, and flowering time regulation. Examining such diverse signal integration dynamics could enhance our understanding of the underlying genetic, biochemical, and molecular mechanisms of ABA signaling networks in plants.decreases after rehydration. In addition, ABA has been considered a long-distance stress signal between shoots and roots [22]. Therefore, the study of spatiotemporal expression of genes that control ABA metabolism rate-limiting steps is essential for understanding how plants adapt to stress. Other than its role in adaptation to abiotic stress, ABA has been shown to be a key regulator of pathogen-virulence [23][24][25][26][27], which could offer insights into the basis of the ABA-synthesizing ability of numerous bio-and necrotrophic microbes [24,[28][29][30].Gene products acting in the vicinity of the cell wall or at the interface of the plasma membrane/cytoskeleton/cell wall are considered the most likely elements to participate in initial stress perception. For instance, gated aquaporins (PIPs, plasma membrane intrinsic proteins) and osmo-/ion channels at the cell wall-plasma membrane interface may be implicated in the upstream perception [31][32][33]. The receptor of ABA remained unknown until 2009. Before 2009, several ABA receptors had been reported [34][35][36][37][38][39][40]; however, further investigations, did not substantiate any of them. In 2009, two independent studies reported the START (steroidogenic acute regulatory protein (StAR)-related lipid-transfer) domain of the significant Bet v1 (birch pollen allergen) superfamily of proteins as candidate ABA receptors [41][42][43][44]. All 14 members of the protein family are named Regulatory Component of ABA Receptor, RCAR1-RCAR14, [41], or Pyrabactin Resistance 1 and PYR1-like 1-13 [42]. The discovery of PYR1-like components ...

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The Antagonistic Action of Abscisic Acid and Cytokinin Signaling Mediates Drought Stress Response in Arabidopsis

Cited by 204 publications

References 65 publications

Cytokinin at the Crossroads of Abiotic Stress Signalling Pathways

Cytokinin at the Crossroads of Abiotic Stress Signalling Pathways

Root-derived trans-zeatin cytokinin protects Arabidopsis plants against photoperiod stress

Integration of Abscisic Acid Signaling with Other Signaling Pathways in Plant Stress Responses and Development

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