The Anatomy of the Trabecular Meshwork as Seen in Tangential Section

Flocks, Milton

doi:10.1001/archopht.1956.00930040716010

Cited by 83 publications

(23 citation statements)

References 9 publications

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“…This was as expected from observations with scanning electron microscopy and other classical histologic techniques. The size of the fluid spaces decreased near Schlemm's canal, again confirming findings using standard 2-D techniques (Flocks 1956). Interconnections between the fluid spaces created continuous pathways for aqueous outflow between the anterior chamber and Schlemm's canal (Theobald 1955).…”

Section: Discussionsupporting

confidence: 78%

Three‐dimensional reconstruction of aqueous channels in human trabecular meshwork using light microscopy and confocal microscopy

et al. 1997

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Summary:Conventional two-dimensional imaging of the trabecular meshwork (TM) provides limited information about the size, shape, and interconnection of the aqueous channels within the meshwork. Understanding the three-dimensional (3-D) relationships of the channels within this tissue may give insight into its normal function and possible changes present in the eye disease glaucoma. The purpose of our study was to compare laser scanning confocal microscopy with standard 1 µm Araldite-embedded histologic sections for 3-D analysis of the trabecular meshwork. In addition, the study was done to determine whether computerized 3-D reconstruction could isolate the fluid spaces of the trabecular meshwork and determine the size of interconnections between the fluid spaces. Confocal microscopy appears comparable to 1 µm Aralditeembedded tissue sections and has the advantage of inherent registration of the serial tissue sections. Three-dimensional reconstruction allowed the isolation of the fluid spaces within the trabecular meshwork and revealed the presence of numerous interconnections between larger fluid spaces. The distribution of these interconnections was randomly arranged, with no predilection for specific regions within the trabecular meshwork. This distribution of constrictions and "expansion chambers" may provide a clue to the mechanism by which subtle histologic changes are associated with increased ocular pressure in glaucoma.

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Section: Discussionsupporting

confidence: 78%

Three‐dimensional reconstruction of aqueous channels in human trabecular meshwork using light microscopy and confocal microscopy

et al. 1997

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“…15 The cribriform plexus has a porelike or reticular appearance when viewed in a tangential orientation. 16,17 The cribriform plexus extends from type A, B, and C tendons that originate from the ciliary muscle tips. 17,18 Type A tendons anchor the longitudinal fibers of the ciliary muscle, type B tendons pass through the trabecular meshwork and anchor in the cornea, and type C tendons enter the fiber system at the outermost corneoscleral meshwork and make a 90°turn before joining the cribriform plexus.…”

mentioning

confidence: 99%

The Elastin Fiber System between and Adjacent to Collector Channels in the Human Juxtacanalicular Tissue

Hann

Fautsch

2011

Invest. Ophthalmol. Vis. Sci.

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Elastin, elaunin, oxytalan, and elastin-associated proteins fibrillin-1 and microfibrillar-associated protein-1/2 were identified within the juxtacanalicular tissue of the inner and outer walls and within collector channel walls of human eyes perfused at low and high pressure. No differences in labeling patterns for elastin, elaunin, and oxytalan were found in the juxtacanalicular tissue adjacent to or between collector channel orifices. The elastin fiber system appears to have a significant role in the support and distensibility of the juxtacanalicular region under collector channels.

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“…Ever since Virchow [1910] distinguished in it an external part or sclerocorneal trabecula, located in the vicinity of Schlemm's canal, and another internal or uveal trabecula, this nomenclature has been accepted by most authors [Allen et al. 1955;Flocks. 1956;Ashton et al.…”

Section: Introductionmentioning

confidence: 99%