1927
DOI: 10.3181/00379727-24-3396
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The Anamnestic Reaction: Response of Previously Immunized Animals to Heterologous Antigens.

Abstract: University, and the Pressb ytenhn Hospital. Cole' observed, in 1904, that after an animal has been immunized subsequent injection of the same antigen causes antibodies to appear eqrlier than after the first injection. Previously immunized animals also show circulating antibodies after the injection of amounts of homologous antigen which, in animals injected for the first time, are insufficient to cause the appearance of demonstrable antibodies. A clinical counterpart of these experiments has been observed in w… Show more

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