2014
DOI: 10.24297/jac.v10i1.5587
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The Analytical Applications And Biological Activity of Hydroxamic acids

Abstract: Hydroxamic acids play a vital role in applied chemistry , the present literature review is an investigation on the analytical applications and biological activity of hydroxamic acids .The review includes a survey of  the historical background of hydroxamic acids , their general structure , classification , physical properties , stability and occurrence in nature .  In addition the review discuss the synthesis and  identification of hydroxamic acids ,in which different methods of synthesis and different analyti… Show more

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Cited by 6 publications
(6 citation statements)
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“…The knowledge of the many medicinal powers of plants has been passed down through the generations through trial and error (Mendoza et al) [8]. A variety of halophytes have been used in various applications (Abualreish and Abdein) [9]. Plant-derived secondary metabolites are used as medicaments to meet the basic needs of people and animals (Osman and Abdein [10] [11], Jamshidi-Kia et al [12]).…”
Section: Introductionmentioning
confidence: 99%
“…The knowledge of the many medicinal powers of plants has been passed down through the generations through trial and error (Mendoza et al) [8]. A variety of halophytes have been used in various applications (Abualreish and Abdein) [9]. Plant-derived secondary metabolites are used as medicaments to meet the basic needs of people and animals (Osman and Abdein [10] [11], Jamshidi-Kia et al [12]).…”
Section: Introductionmentioning
confidence: 99%
“…Hydroxamic acids are weakly acidic, primarily due to the ‐OH group (p K a 8–9). They are weaker acids than their corresponding carboxylic acids (p K a 4–5), but more acidic than the amides (p K a 20–22) …”
Section: Hydroxamic Acidsmentioning
confidence: 99%
“…They are weaker acids than their corresponding carboxylic acids (pK a 4-5), but more acidic than the amides (pK a [20][21][22]. [23,24] HAs are capable of acting as mono-or bidentate ligands through the oxygen atoms, but can more rarely also act as monodentate ligandst hrough the nitrogen atom, if unsubstituted. [18,25] The loss of ap rotonf rom the hydroxy group, followed by ar ing closing by the carbonyl allows for the formation of as table five-membered metallacycle duringm etal coordination.…”
Section: Hydroxamic Acidsmentioning
confidence: 99%
“…It has been used in traditional medicine, especially in Arab lands for a long time. It has many medical and economic benefits as ant nociceptive activity [28], source for saponins, free sugar, proteins and antidiarrheal effects [29] [30], protective effect against aflatoxicosis [31], treatment pain [32], rich source of flavonoids [33] [34], source for lipids, triterpenoids, alkaloids, free radical scavenging potential and antioxidant activity [35] [36] [37], the hypolipidemic and antioxidant activity [38], antimicrobial activity [39] [40] [41] [42], anti-inflammatory [43] and antibacterial activity [44] [45], Anticancer activity [46] [47] [48] [49], Antidiabetic Potentiality [50], Antiviral activity [51].…”
Section: Introductionmentioning
confidence: 99%