The amygdala and intractable temporal lobe epilepsy

Abstract

The combination of AT2 mapping and FLAIR is a sensitive method to detect lesions that are not seen on routine MRI in the amygdalae of patients with intractable TLE. Further correlational studies will be required to define the role of this technique in the presurgical evaluation of patients with intractable TLE.

Preserved verbal memory function in left medial temporal pathology involves reorganisation of function to right medial temporal lobe

“…In patients with HS, the amygdala may be affected by the same sclerotic pathology as the hippocampus, although the severity of hippocampal and amygdala sclerosis in a given patient may be uncorrelated (Hudson et al, 1993). As in the case of the hippocampus, amygdala pathology may be assessed using MRI by measuring T2 signal (Van Paesschen et al, 1996;Bartlett et al, 2002).…”

Yield of Fluid-Attenuated Inversion Recovery in Drug-Resistant Focal Epilepsy with Noninformative Conventional Magnetic Resonance Imaging

“…We did not observe any high signal in the amygdala whilst Bergin et al [11]reported 5 patients with high signals located in that structure. High signals visible in the amygdala on fast FLAIR sequences have recently been described by Van Paesschen et al [20]. In our study, none was reported probably because these lesions were detected on conventional MRI and the corresponding patients would subsequently have been excluded from this study.…”

T 2 : The Transverse Relaxation Time

“…T 2 -mapping of the amygdala (AT2) has therefore been applied in patients with epilepsy (Kalviainen et al, 1997a). The principle is similar to HCT2 mapping, but the orientation is a tilted axial plane, allowing the evaluation of the amygdala independently of the hippocampus (Van Paesschen et al, 1996). In a study of patients with TLE, abnormal AT2 ipsilateral to the seizure focus was seen in 52 % of patients.…”