The Amounts of Glycerylphosphorylcholine in Some Mammalian Tissues

Schmidt, Gerhard; Hecht, Liselotte I.; Fallot, P; Greenbaum, Lowell M.; Thannhauser, S. J.

doi:10.1016/s0021-9258(18)55614-3

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1954

1984

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Cited by 27 publications

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“…It was over a quarter century ago that Schmidt et al first reported GPC to be present in several tissues (Schmidt et al, 1945). However, subsequent work by the same group (Schmidt et al, 1952) has found only negligible amounts of GPC in beef muscle. Our NMR studies reveal high levels of GPC in intact slow twitch and heart muscles in contrast to fast twitch muscles which essentially lack this compound.…”

Section: Discussionmentioning

confidence: 99%

Phosphorus-31 nuclear magnetic resonance detection of unexpected phosphodiesters in muscle

Burt¹,

Glonek²,

Bárány³

1976

Biochemistry

160

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In the examination of intact muscles by 31P nuclear magnetic resonance spectroscopy, a number of signals have been detected in the phosphodiester region (-0.5 to 0.5 ppm) of the spectrum which could not be correlated with the known common phosphates of muscle tissue. These signals arise from perchloric acid extractable compounds with several common chemical properties, one of which is a ready solubility in nearly anhydrous ethanol solutions. A component contributing to the major resonance has been identified as glycerol-3-phosphorylcholine. This characterization is based on both 31P nuclear magnetic resonance and chromatographic data.

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Section: Discussionmentioning

confidence: 99%