often describe the 3 greatest assets of the American Heart Association (AHA) as our brand, our grassroots volunteers, and our science. Each is critical to our mission, but without science, we would not be the same organization. We were founded by scientists who sought new insights into heart disease. Now, 100 years later, we remain squarely focused on the power of science and research to improve and extend lives. Our milestone birthday is a perfect opportunity to reflect on our many lifesaving accomplishments along our journey to treat and prevent the 2 leading causes of death worldwide: heart disease and stroke.