The ameliorating effects of apigenin and chrysin alone and in combination on polycystic ovary syndrome induced by dehydroepiandrosterone in rats
Buket Berk,
Nevin İlhan,
Solmaz Susam
et al.
Abstract:Objective: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is
one of the main causes of ovulation infertility, affecting 5-10% of women. Inflammation, hormonal imbalances, and disruption of the
oxidant-antioxidant balance are the main factors in the pathophysiology of PCOS. This study was designed to answer the question of
whether apigenin and chrysin have therapeutic effects on the dehydroepiandrosterone (DHEA)-induced rat model of PCOS.
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