The ambulatory arterial stiffness index is not affected by night-time blood pressure characteristics

Vincenti, Marie; Vigier, Rodo O. von; Wühl, Elke; Mohaupt, Markus; Simonetti, Giacomo D.

doi:10.1038/jhh.2009.25

Cited by 6 publications

(5 citation statements)

References 12 publications

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“…Indeed, in accordance with previous reports, daytime AASI calculated from awake ambulatory measurements was higher compared to 24-h AASI. 20 However, HASI in this study remained significantly higher than daytime AASI (Figure 1). Second, HASI is based on BP measurements taken under strictly standardized conditions of posture and activity (in the sitting posture and after a few minutes rest), whereas AASI is based on measurements taken in ambulatory conditions while subjects undertake their usual daily activities.…”

Section: Diagnostic Agreement Studiescontrasting

confidence: 52%

“…These data also confirm previous reports that daytime AASI is higher than 24-h AASI. 20 It might therefore be argued that because HASI is exclusively derived from morning and evening BP measurements, each time in duplicate but within a short time interval, this index provides only limited information for the dynamic relationship of systolic with diastolic BP. On the other hand, AASI is based on measurements obtained in a wide range of physical activity levels (during a variety of daily activities, at work, at home and during sleep), as well as measurements in the transition periods between wakefulness and sleep (nocturnal BP dip and morning surge).…”

Section: Diagnostic Agreement Studiesmentioning

confidence: 99%

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Arterial stiffness index based on home (HASI) vs. ambulatory (AASI) blood pressure measurements

et al. 2010

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Ambulatory arterial stiffness index (AASI) is a novel index derived from the linear relationship between 24-h ambulatory systolic and diastolic blood pressure (BP) measurements. This study investigated whether 'home arterial stiffness index' (HASI) based on self-home BP measurements is similar to AASI. A total of 483 hypertensive subjects underwent 24-h ambulatory and 6-day home BP monitoring. AASI and HASI were defined as one minus the respective regression slope of diastolic on systolic BP. Mean HASI (0.66±0.17) was higher than 24-h (0.33±0.15) daytime (0.50±0.18) and nighttime AASI (0.37±0.19, Po0.001 for all comparisons vs. HASI) and was weakly correlated with 24-h (r¼0.14, Po0.01) daytime (r¼0.14, Po0.01) and nighttime AASI (r¼0.09, P¼0.05). Compared to 24-h AASI, HASI was less closely associated with age (r¼0.46 and 0.10 respectively, Po0.001 for difference), systolic home BP (r¼0.30 and 0.09, Po0.001) and pulse pressure (r¼0.52 and 0.20, Po0.001), as well as with 24-h ambulatory systolic BP (r¼0.21 and 0.05, Po0.05) and pulse pressure (r¼0.56 and 0.25, Po0.001). No satisfactory agreement was observed between HASI and 24-h (agreement 63%, j 0.02) daytime (agreement 65%, j 0.1) or nighttime AASI (agreement 63%, j 0.03) in detecting subjects at the top quartile of the respective distributions. HASI appears to be similar but also has important differences from AASI and is less closely associated with markers of arterial stiffness. These data do not support the view that home BP measurements can replace ambulatory monitoring in the assessment of the arterial stiffness index.

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Section: Diagnostic Agreement Studiescontrasting

confidence: 52%

Section: Diagnostic Agreement Studiesmentioning

confidence: 99%

Arterial stiffness index based on home (HASI) vs. ambulatory (AASI) blood pressure measurements

et al. 2010

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“…150 In children, the AASI was found to be elevated in hypertensive children. 54,151 Although interesting, these advanced calculations remain feasible only in a research setting.…”

Section: Methods For Performance Of Abpmmentioning

confidence: 99%

Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents

Flynn¹,

Daniels²,

Hayman³

et al. 2014

Hypertension

533

417

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“…First, we used AASI and s-AASI as indirect indicators of arterial stiffness, rather than direct measuring techniques such as pulse wave velocity and flow-mediated dilation. However, while AASI may exhibit a strong inverse relationship with degree of nocturnal BP fall, 19,30 heart rate, 31 and ambulatory monitoring, 32 it is widely applied as a measure of arterial stiffness/compliance, [22][23][24] and correlates with classical measures of arterial stiffness such as pulse wave velocity, 20,25 central and peripheral pulse pressure, 26 and systolic augmentation index. 27 Results of s-AASI are reported to be more clinically relevant with greater predictive power than AASI.…”

Section: Limitationsmentioning

confidence: 99%

“…27 It also provides prognostic information on cardiovascular mortality and targetorgan damage over a wide range of ages, especially in normotensive individuals. 28,29 However, AASI has been criticized for its strong inverse relationship with the degree of nocturnal BP fall, 19,30 heart rate, 31 and its ambulatory monitoring technique. 32 Recently, a modified, symmetric ambulatory arterial stiffness index (s-AASI) has been shown to provide more clinically relevant evaluation of arterial stiffness, with greater predictive power than the previously established AASI parameter.…”

mentioning

confidence: 99%

Salt Loading and Potassium Supplementation: Effects on Ambulatory Arterial Stiffness Index and Endothelin‐1 Levels in Normotensive and Mild Hypertensive Patients

Liu

Peng

et al. 2013

J of Clinical Hypertension

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2The authors investigated effects of excessive salt intake and potassium supplementation on ambulatory arterial stiffness index (AASI) and endothelin-1 (ET-1) in salt-sensitive and nonsalt-sensitive individuals. AASI and symmetric AASI (s-AASI) were used as indicators of arterial stiffness. Plasma ET-1 levels were used as an index of endothelial function. Chronic salt-loading and potassium supplementation were studied in 155 normotensive to mild hypertensive patients from rural northern China. After 3 days of baseline investigation, participants were maintained sequentially for 7 days each on diets of low salt (51.3 mmol/d), high salt (307.7 mmol/d), and high salt+potassium (60 mmol/d). Ambulatory 24-hour blood pressure (BP) and plasma ET-1 were measured at baseline and on the last 2 days of each intervention. High-salt intervention significantly increased BP, AASI, s-AASI (all P<.001); potassium supplementation reversed increased plasma ET-1 levels. High-salt-induced changes in BP, s-AASI, and plasma ET-1 were greater in salt-sensitive individuals. Potassium supplementation decreased systolic BP and ET-1 to a significantly greater extent in salt-sensitive vs non-salt-sensitive individuals (P<.001). Significant correlations were identified between s-AASI and ET-1 change ratios in response to both high-salt intervention and potassium supplementation (P<.001). Reducing dietary salt and increasing daily potassium improves arterial compliance and ameliorates endothelial dysfunction.

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The ambulatory arterial stiffness index is not affected by night-time blood pressure characteristics

Cited by 6 publications

References 12 publications

Arterial stiffness index based on home (HASI) vs. ambulatory (AASI) blood pressure measurements

Arterial stiffness index based on home (HASI) vs. ambulatory (AASI) blood pressure measurements

Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents

Salt Loading and Potassium Supplementation: Effects on Ambulatory Arterial Stiffness Index and Endothelin‐1 Levels in Normotensive and Mild Hypertensive Patients

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