The aging auditory system: anatomic and physiologic changes and implications for rehabilitation

Chisolm, Theresa H.; Willott, James F.; Lister, Jennifer J.

doi:10.3109/14992020309074637

Cited by 111 publications

(92 citation statements)

References 66 publications

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“…Despite firm evidence for sensitive periods, hearing lossinduced changes to central auditory function are also well documented in adulthood, especially during senescence (Syka, 2002(Syka, , 2010Chisolm et al, 2003;Caspary et al, 2008;Turner et al, 2013). Regardless of age of onset, both short-and long-term auditory deprivation are associated with measurable changes in sensory and cognitive function Formby et al, 2003;Munro and Blount, 2009;Lin et al, 2011;Seldran et al, 2011;.…”

Section: Discussionmentioning

confidence: 99%

A Sensitive Period for the Impact of Hearing Loss on Auditory Perception

Buran¹,

Sarro²,

Manno³

et al. 2014

J. Neurosci.

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Manipulations of the sensory environment typically induce greater changes to the developing nervous system than they do in adulthood. The relevance of these neural changes can be evaluated by examining the age-dependent effects of sensory experience on quantitative measures of perception. Here, we measured frequency modulation (FM) detection thresholds in adult gerbils and investigated whether diminished auditory experience during development or in adulthood influenced perceptual performance. Bilateral conductive hearing loss (CHL) of Ϸ30 dB was induced either at postnatal day 10 or after sexual maturation. All animals were then trained as adults to detect a 5 Hz FM embedded in a continuous 4 kHz tone. FM detection thresholds were defined as the minimum deviation from the carrier frequency that the animal could reliably detect. Normal-hearing animals displayed FM thresholds of 25 Hz. Inducing CHL, either in juvenile or adult animals, led to a deficit in FM detection. However, this deficit was greater for juvenile onset hearing loss (89 Hz) relative to adult onset hearing loss (64 Hz). The effects could not be attributed to sensation level, nor were they correlated with proxies for attention. The thresholds displayed by CHL animals were correlated with shallower psychometric function slopes, suggesting that hearing loss was associated with greater variance of the decision variable, consistent with increased internal noise. The results show that decreased auditory experience has a greater impact on perceptual skills when initiated at an early age and raises the possibility that altered development of CNS synapses may play a causative role.

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Section: Discussionmentioning

confidence: 99%

A Sensitive Period for the Impact of Hearing Loss on Auditory Perception

Buran¹,

Sarro²,

Manno³

et al. 2014

J. Neurosci.

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“…A flat audiometric loss like the one in our study can be ascribed to metabolic presbyacusis (Dubno et al 2013;Humes et al 2012;Schmiedt 2010). However, it is difficult and not reliable to diagnose the form of ARHL solely based on the shape of the audiogram (Chisolm et al 2003;Ohlemiller 2004). Thus, further studies are necessary to clarify the reasons and mechanisms of the decrease in hearing sensitivity described in this study.…”

Section: Effects Of Agingmentioning

confidence: 56%

“…Since the description of four types of human presbyacusis by Schuknecht (1974), research in this field has expanded and his framework has been widely discussed (Chisolm et al 2003;Ohlemiller 2004;Schmiedt 2010). When comparing the general shape of the auditory thresholds of young and old gray mouse lemurs, it is noticeable that it does not change.…”

Section: Effects Of Agingmentioning

confidence: 99%

Hearing and Age-Related Changes in the Gray Mouse Lemur

Schopf

Zimmermann

Tünsmeyer

et al. 2014

JARO

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In order to examine auditory thresholds and hearing sensitivity during aging in the gray mouse lemur (Microcebus murinus), suggested to represent a model for early primate evolution and Alzheimer research, we applied brainstem-evoked response audiometry (BERA), traditionally used for screening hearing sensitivity in human babies. To assess the effect of age, we determined auditory thresholds in two age groups of adult mouse lemurs (young adults, 1-5 years; old adults, ≥7 years) using clicks and tone pips. Auditory thresholds indicated frequency sensitivity from 800 Hz to almost 50 kHz, covering the species tonal communication range with fundamentals from about 8 to 40 kHz. The frequency of best hearing at 7.9 kHz was slightly lower than that and coincided with the dominant frequencies of communication signals of a predator. Aging shifted auditory thresholds in the range between 2 and 50.4 kHz significantly by 12-27 dB. This mild presbyacusis, expressed in a drop of amplitudes of BERA signals, but not discernible in latencies of responses, suggests a metabolic age-related decrease potentially combined with an accompanying degeneration of the cochlear nerve. Our findings on hearing range of this species support the hypothesis that predation was a driving factor for the evolution of hearing in small ancestral primates. Likewise, results provide the empirical basis for future approaches trying to differentiate peripheral from central factors when studying Alzheimer's disease-like pathologies in the aging brain.

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“…Primeiro, o efeito negativo do ruído no reconhecimento de fala, mesmo para idosos sem perda auditiva, fato já observado na literatura 8,11,12 . O segundo aspecto está relacionado ao fato de o envelhecimento não se limitar apenas ao órgão de Corti (audição periférica), mas a todo o sistema auditivo [24][25][26] . Assim, mesmo a ausência de uma perda auditiva, detectada no exame de audiometria tonal, não garante um desempenho adequado quanto ao reconhecimento de fala.…”

Section: Comparação Dos Tipos De Troca E Omissão No Teste F/r Para O unclassified

Percepção de fala em idosos: análise dos erros

Calais

Russo

Borges

2010

Rev. bras. geriatr. gerontol.

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OBJETIVO: analisar os erros apresentados em um teste de fala na presença de ruído competitivo de idosos. MÉTODO: foi realizado estudo retrospectivo com levantamento de dados de prontuário de 55 idosos divididos em grupo controle (GC) e grupo estudo (GE), considerando os testes Índice Percentual de Reconhecimento de Fala (IPRF) e Fala com Ruído (F/R). RESULTADO: as trocas articulatórias foram mais frequentes no GE e no teste F/R. De maneira geral, ocorreram mais omissões de fonemas na posição inicial (/p/ e /b/) e final (/s/) dos vocábulos, principalmente com o ruído. Houve omissões de vocábulos somente no GE. Os vocábulos mais trocados no GC foram "rir ", "dil ", "lhe ", "faz " e "rol ", e no GE, "rir ", "dil ", "lhe ", "faz ", "pus " e "rol ". CONCLUSÃO: a presença de limiares tonais normais não impediu que ocorressem erros no reconhecimento de fala e o ruído interferiu negativamente neste reconhecimento, principalmente no idoso com perda auditiva. Os fonemas /p/, /b/ e /s/ foram os mais frequentemente omitidos, principalmente na presença do ruído competitivo. Os vocábulos "rir ", "dil ", "lhe ", "faz " e "rol " foram os mais trocados para os grupos avaliados, sobretudo na presença do ruído.

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The aging auditory system: anatomic and physiologic changes and implications for rehabilitation

Cited by 111 publications

References 66 publications

A Sensitive Period for the Impact of Hearing Loss on Auditory Perception

A Sensitive Period for the Impact of Hearing Loss on Auditory Perception

Hearing and Age-Related Changes in the Gray Mouse Lemur

Percepção de fala em idosos: análise dos erros

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