The age-specific reference intervals for tPSA, fPSA, and %fPSA in healthy Han ethnic male

Abstract

We established age-specific RIs for tPSA, fPSA and %fPSA. The newly established RIs should be more suitable for Chinese Han ethnic male. It will be valuable for physicians to make exact medical decision and appropriate medical intervention.

Determination of Reference Interval of Tumour Markers in Kahramanmaraş Region, Turkey

“…They suggested that their reference intervals were more appropriate for Chinese males (33). Yang et al highlighted variability in reference limits according to the diversity in the population, geographic characteristics, living conditions, measurement systems, and analytical methods (35). Upper limits determined in the present study are different than those reported in other studies.…”

Establishment of the reference interval for serum pro-gastrin-releasing peptide in healthy adults of Chinese Han ethnicity

“…The RI is required for the interpretation of clinical laboratory results and patient care. [11][12][13][14][15] In fact, the RI for serum proGRP using TR-IFMA has been reported in a healthy Nordic population. 9 In healthy adults of Chinese Han ethnicity, the RIs for plasma ProGRP by CMIA on the Abbot ARCHITECT i2000 system also have been established.…”

The Clinical Usefulness of Prostate Cancer Biomarkers: Current and Future Directions

“…Results from that study highlighted that there was a gradual increase in reference interval for tPSA and fPSA peaking at 7.73 and 2.41 ng/ mL respectively for those over 80 years old. The researchers also reported that reference intervals for %fPSA were ≥16.0 for 21-50 years and ≥13.0 for males over 50 years old [56]. In a South American study of over 17,000 men, %fPSA value of <15 as an indication for biopsy was shown to increase the rate of PCa detection in patients with normal DRE results and serum tPSA of 2.5-4.0 ng/mL [17].…”