The Aetiology of Enteric Fever in Abuja, North Central Nigeria

Abstract

Enteric fever is caused by Salmonella enterica serotype typhi, Salmonella paratyphi A, B, C, and Salmonella typhimurium respectively. Of the 2818 blood cultures reviewed, only 90 (3.2%) had positive cultures for Salmonella species while the 10,007 faecal samples cultured, 159 (1.6%) were positive for Salmonella species. Identification of isolates was by usual bacteriological techniques including biochemical and serological methods. Percentage occurrence of Salmonella species in blood and faecal samples show Salmonella enterica serotype typhi (75.6% and 59.8%), Salmonella paratyphi A (4.4% and 9.4%), Salmonella paratyphi B (17.8% and 19.5%), Salmonella paratyphi C (2.2% and 6.3%) and Salmonella typhimurium (0.0% and 5.0%). The susceptibility pattern of all the isolates to the eleven drugs used as listed on table iii is highly revealing. For epidemiological status and proper management of patients, it is necessary that appropriate specimens (blood, bone marrow and faecal cultures) are examined and identification of isolates carried out as well as proper sensitivity testing performed prior to treatment for enteric fever.