1994
DOI: 10.1097/00000542-199409001-00234
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The Adrenergic Response to Mild Core Hypothermia

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Cited by 3 publications
(3 citation statements)
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“…Thirdly, our volume of cold infusion in protocol 1 may have been sufficient to change cardiopulmonary volumes and pressures. However, a similar volume of warm saline was not shown to change blood pressure, heart rate or H RV [31]. Therefore, it is unlikely that the effect we observed was due to the fluid infusion, but rather due to the change in core temperature.…”
Section: Protocol 2: Skin-surface Coolingmentioning
confidence: 60%
See 1 more Smart Citation
“…Thirdly, our volume of cold infusion in protocol 1 may have been sufficient to change cardiopulmonary volumes and pressures. However, a similar volume of warm saline was not shown to change blood pressure, heart rate or H RV [31]. Therefore, it is unlikely that the effect we observed was due to the fluid infusion, but rather due to the change in core temperature.…”
Section: Protocol 2: Skin-surface Coolingmentioning
confidence: 60%
“…The response to cold challenge involves afferent input of temperature information to the hypothalamic centres, central processing of this information and an efferent response [30]. This efferent response is characterized by peripheral sympathetic activation as indicated by increased noradrenaline, but no adrenal medullary or cortical activation as determined by adrenaline and cortisol [24,31]. The peripheral sympathetic activation is marked by profound vasoconstriction, as demonstrated by an increase in the forearmfingertip temperature gradient [23].…”
Section: Protocol 2: Skin-surface Coolingmentioning
confidence: 99%
“…The a-adrenergic antagonist-induced 'selective' inhibition of vasomotor tone in the absence of changes in metabolic heat production suggests that the two thermoregulatory responses occur by different mechanisms. Previous studies have shown that vasoconstriction [17][18][19] and non-shivering thermogenesis [20] are mediated by catecholamines. There is some evidence for an adrenergic mechanism contributing to the metabolic response during cold challenge, with adrenaline contributing more than noradrenaline to the shivering response [21].…”
Section: Variablementioning
confidence: 98%