The Adjustment of Oxygen Uptake at the Onset of Exercise: Relation to Age and to Work Load

Mácek, M; Vavra, James J.; Benešová, Hana; Radvanský, J.

doi:10.1007/978-3-642-69465-3_16

Cited by 5 publications

(3 citation statements)

References 2 publications

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“…That trend was similar to reference data for healthy girls, but the absolute values in our patients were lower. 6 Same finding was reported by Müller et al . in 57 paediatric TCPC patients.…”

Section: Discussionsupporting

confidence: 66%

Exercise capacity after total cavopulmonary anastomosis: a longitudinal paediatric and adult study

et al. 2021

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Aims Fontan palliation is a surgical strategy for patients with complex congenital heart disease, in whom biventricular circulation cannot be achieved. Long‐term survival is negatively affected by the absence of sub‐pulmonary ventricle and increased systemic venous pressure. Exercise capacity is a known predictor of overall survival and quality of life in congenital heart defects. We aim to track individual trends of peak oxygen uptake (V̇O2peak) after total cavopulmonary connection (TCPC), identify predictors of deterioration, and derive a disease‐specific reference V̇O2peak dataset. Methods and results A retrospective study of serial cardiopulmonary exercise testing (CPET) data, gathered from all patients who underwent TCPC in the Czech Republic between 1992 and 2016. Of 354 consecutive patients with TCPC, 288 (81.4%) patients underwent one or more CPETs yielding 786 unique V̇O2peak values used as a reference dataset. Longitudinal data were available in 206 (58.2%) patients, who underwent a median (inter‐quartile range) of 3.0 (2.0–5.0) CPETs over a mean (standard deviation) of 8.9 (5.5) years. The decline of exercise capacity with age was linear and not faster than in healthy peers (P = 0.47), but relative values of V̇O2peak in TCPC patients were 12.6 mL/min/kg lower. Single ventricular morphology and pulmonary artery size had no significant influence on the exercise capacity dynamics. V̇O2peak decline correlated negatively with the trend of body mass index z‐score (P = 0.006) and was faster in women than men (P = 0.008). Conclusions Total cavopulmonary connection patients have significantly reduced exercise capacity. The age‐related decline paralleled the healthy population and correlated negatively with the body mass index trend. The presented V̇O2peak reference dataset may help the clinicians to grade the severity of exercise capacity impairment in individual TCPC patients.

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Section: Discussionsupporting

confidence: 66%

Exercise capacity after total cavopulmonary anastomosis: a longitudinal paediatric and adult study

et al. 2021

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“…According to Cooper et al (10), \V02 kinetics at the onset of exercise are the same in children and adults when the work performed is below the lactate threshold. Other authors report faster c702 kinetics in children than in adults (18,23,32,33,34) and a higher aerobic contribution during the Wingate test in childhood (41). Furthermore, acute or chronic hypoxia (31,37) does not modify significantly performances obtained during a 30-s Wingate test in adults and hypoxia decreases \VO2max in adults (8,14) as in children (15,20) whereas 02 inhalation increased VO2max for subjects living at high altitutde (7).…”

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confidence: 94%

The Effect of Acute Hypoxia at Low Altitude and Acute Normoxia at High Altitude on Performance During a 30-s Wingate Test in Children

Blonc¹,

Falgairette²,

Boccadoro³

et al. 1994

Int J Sports Med

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The effect of acute hypoxia (FIO2 = 0.137 +/- 0.001) at Low Altitude (LA: Clermont-Ferrand, 330 m) and acute normoxia (FIO2 = 0.306 +/- 0.006) at High Altitude (HA: La Paz, 3600 m) on performance during a 30-s Wingate test has been investigated in prepubertal children (Tanner stage 1). Twenty five boys (LA, n = 10; HA, n = 15) aged from 10.6 to 12.7 years performed two Wingate tests at random: at LA, one in normoxia (ambient air) and one in acute hypoxia and at HA, one in chronic hypoxia (ambient air) and one in acute normoxia. The subjects performed the two tests using the same calibrated cycle ergometer. Peak Power (PP), Mean Power (MP), O2 uptake during the 30 s (VO2) and blood lactate accumulation (delta [L]s) were measured. Compared to normoxia, acute hypoxia at LA did not alter PP (8.0 +/- 1.1 vs 7.9 +/- 1.3 W.kg-1 BW) and MP (6.1 +/- 0.7 vs 6.1 +/- 1.1 W.kg-1 BW). Similarly, compared to chronic hypoxia, acute normoxia at HA did not modify these parameters (PP: 7.4 +/- 1.5 vs 7.3 +/- 1.8; MP: 5.4 +/- 1.2 vs 5.5 +/- 1.1; W.kg-1 BW). VO2 and delta [L]s were neither significantly changed by acute hypoxia at LA (520 +/- 50 vs 550 +/- 60 ml O2; 5.3 +/- 1.7 vs 4.8 +/- 1.7 mmol.l-1) nor by acute normoxia at HA (530 +/- 110 vs 500 +/- 90 ml O2; 3.4 +/- 1.3 vs 3.3 +/- 1.0 mmol.l-1).(ABSTRACT TRUNCATED AT 250 WORDS)

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“…If we compile knowledge about aging and old age from various clinical disciplines of human medicine, we come to the information that aging is based on both genetic information and the acquired external and internal influences. Every person has a certain performance genetically given (Máček, Radvanský et al, 2011). Physiological aging is a universal process that begins in the third decade.…”

Section: Introductionmentioning

confidence: 99%

Active life style in senior age - How to live healthily and wisely – longevity in a good european style

Górna-Łukasik,

Grzybowska

2020

ASV

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The aim of the presented study is to analyse and evaluate the significance of the lifelong contribution of prof. Jan Ślężyński for the support of active lifestyle in senior age, especially how he copes with the difficult aspects of old age - how to live healthily and wisely in a context of health support and wellness in European style. The partial goal is to capture autobiographical attributes in the context of the chosen topic. Methods as: Case study method; Content analysis; Hysteresis; Descriptive analysis were applied. Regular physical activity in senior age prevents atrophy of muscle as well as muscle strength and cardiorespiratory function. The risk of premature death with a change from a sedentary lifestyle to a physically active life is a prerequisite for a long and healthy life. During the active life style promoting human health through properly applied movement, prof. Jan Ślężyński represents the importance of an active lifestyle in senior age as a prerequisite for a long and healthy life.

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The Adjustment of Oxygen Uptake at the Onset of Exercise: Relation to Age and to Work Load

Cited by 5 publications

References 2 publications

Exercise capacity after total cavopulmonary anastomosis: a longitudinal paediatric and adult study

Exercise capacity after total cavopulmonary anastomosis: a longitudinal paediatric and adult study

The Effect of Acute Hypoxia at Low Altitude and Acute Normoxia at High Altitude on Performance During a 30-s Wingate Test in Children

Active life style in senior age - How to live healthily and wisely – longevity in a good european style

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