The adiponectin receptor agonist, AdipoRon, promotes reproductive hormone secretion and gonadal development via the hypothalamic-pituitary-gonadal axis in chickens

ADPN Regulates Oxidative Stress-Induced Follicular Atresia in Geese by Modulating Granulosa Cell Apoptosis and Autophagy

“…[49]. In addition, the ADPN receptor agonist AdipoRon promotes the secretion of reproductive hormones and gonadal development through the hypothalamic-pituitary-gonadal (HPG) axis, and GnRH is an important regulator of the HPG axis [50]. Our aforementioned results suggest that oxidative stress and ADPN have a function in regulating apoptosis.…”

Effects of puerarin as a feed additive on the laying performance, egg quality, endocrine hormones, antioxidant capacity, and intestinal morphology of aged laying hens

“…A dose-dependent relationship between plasma E2 and oviduct growth exists, hence, E2 reflects ovarian follicular development, which in turn predicts future egg production ( Zhang et al, 2021 ). Analogously, P4 is co-regulated by FSH and LH, which are involved in regulating gonadal development and reproduction ( Li et al, 2023 ). Recent evidence has shown that dietary supplementation with 150 mg/kg curcumin increases FSH and LH concentrations in heat-stressed laying hens ( Liu et al, 2020 ).…”

Characterization of reproductive hormones and related gene expression in the hypothalamus and pituitary gland in the egg-laying interval in White King pigeon

“…These hormones are then transported to target the cell membrane, combining with receptors and creating negative feedback in the hypothalamus. This process regulates follicle selection and ovulation ( Yang et al, 2022 ; Li et al, 2023 ). The LH secretion in chickens is stimulated by low-frequency GnRH pulses, whereas FSH secretion is stimulated by high-frequency pulses ( Soñez et al, 2010 ).…”