The addition of nano-sized hydroxyapatite to a sports drink to inhibit dental erosion—In vitro study using bovine enamel

Min, Ji‐Hyun; Kwon, Ho Keun; Kim, Baek Il

doi:10.1016/j.jdent.2011.07.001

Cited by 61 publications

(44 citation statements)

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“…Beside this traditional approach to prevent erosiv and erosiv/abrasive tooth wear by use of fluoride formulation, different complexes of metal cations (e.g. stannous ions) 21 , the use of CO 2 lasers 22 or addition of nano-sized hydroxyapatite 23 and calcium 24 to erosive drinks have been used to find new and more effective formulations and approaches to prevent erosive/abrasive tooth wear. The use of fluorides not only has a protective effect against erosion but also, and maybe more importantly, against caries 25 .…”

Section: Introductionmentioning

confidence: 99%

Long-term protective effect of surface sealants against erosive wear by intrinsic and extrinsic acids

Wegehaupt

Tauböck

Sener

et al. 2012

Journal of Dentistry

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OBJECTIVE: To test sealants to prevent erosive tooth wear caused by extrinsic and intrinsic acids under long-term exposition. METHODS: 144 bovine enamel samples were randomly allocated to twelve groups (1-12). Samples of groups 1, 5 and 9 remained unsealed (positive controls), 2, 6 and 10 were sealed with Silicon Seal Nano Mix and 3, 7 and 11 with SealProtect. Groups 4, 8 and 12 were sealed with flowable composite (negative controls). Groups 1-4 were immersed in artificial saliva, 5-8 in hydrochloric acid and groups 9-12 in citric acid for 28 days, respectively. After 1, 2, 4, 7, 11, 14, 21 and 28 days, solutions were renewed and enamel wear was quantified by assignation of (32)P in the solutions. RESULTS: In all immersion solutions, lowest mineral loss was observed for the negative controls whilst highest loss was observed for unsealed positive controls. In artificial saliva and citric acid, the loss from samples sealed with SealProtect was not significantly different compared with negative controls whilst loss in groups sealed with Silicon Seal Nano Mix was significantly higher. In hydrochloric acid, loss from samples sealed with SealProtect was not different compared with that of negative controls up to 4 days. Except day 1, the mineral loss in the SealProtect group was significantly lower compared with that of the Silicon Seal Nano Mix group. CONCLUSION: The tested resin based surface sealant is able to significantly reduce the erosive demineralisation of enamel caused by hydrochloric and citric acid even under long-term exposition. Abstract:Objective: To test sealants to prevent erosive tooth wear caused by extrinsic and intrinsic acids under long-term exposition.Methods: 144 bovine enamel samples were randomly allocated to twelve groups (1-12). Samples of groups 1, 5 and 9 remained unsealed (positive controls), 2, 6 and 10 were sealed with Silicon Seal Nano Mix and 3, 7 and 11 with Seal&Protect. Groups 4, 8 and 12 were sealed with flowable composite (negative controls).Groups 1-4 were immersed in artificial saliva, 5-8 in hydrochloric acid and groups 9-12 in citric acid for 28 days, respectively. After 1, 2, 4, 7, 11, 14, 21 and 28 days, solutions were renewed and enamel wear was quantified by assignation of 32 P in the solutions.Results: In all immersion solutions, lowest mineral loss was observed for the negative controls while highest loss was observed for unsealed positive controls.In artificial saliva and citric acid, the loss from samples sealed with Seal&Protect was not significantly different compared with negative controls while loss in groups sealed with Silicon Seal Nano Mix was significantly higher.In hydrochloric acid, loss from samples sealed with Seal&Protect was not different compared with that of negative controls up to 4 days. Except day 1, the mineral loss in the Seal&Protect group was significantly lower compared with that of the Silicon Seal Nano Mix group.Conclusion: The tested resin based surface sealant is able to significantly reduce the erosive demineralisation of ename...

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Section: Introductionmentioning

confidence: 99%

Long-term protective effect of surface sealants against erosive wear by intrinsic and extrinsic acids

Wegehaupt

Tauböck

Sener

et al. 2012

Journal of Dentistry

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“…microhardness, analysis of mineral loss or others). Recently, CLSM war applied also to sections of erosive lesion to measure depth of erosive loss and of demineralization [102]. This procedure, however, needs some further validation.…”

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confidence: 99%

Methods for Assessment of Dental Erosion

Attin

Wegehaupt²

2014

Monographs in Oral Science

124

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Various assessment techniques have been applied to evaluate the loss of dental hard tissue and the surface-softened zone in enamel induced by erosive challenges. In this chapter, the most frequently adopted techniques for analyzing the erosively altered dental hard tissues are reviewed, such as profilometry, measuring microscope techniques, microradiography, scanning electron microscopy, atom force microscopy, nano-and microhardness tests and iodide permeability test. Moreover, methods for chemical analysis of minerals dissolved from dental hard tissue are discussed. It becomes evident that the complex nature of erosive mineral loss and dissolution might not be comprehended by a single technique, but needs application of different approaches for full understanding. Chapter 10Lussi A (ed): Dental Erosion. Monogr Oral Sci. Basel, Karger, 2006, vol 20, pp 152-172 Methods for Assessment of Dental Erosion Thomas Attin, Florian Just WegehauptCenter for Dental Medicine, Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zurich, Zürich, Switzerland AbstractVarious assessment techniques have been applied to evaluate the loss of dental hard tissue and the surface-softened zone in enamel induced by erosive challenges. In this chapter, the most frequently adopted techniques for analyzing the erosively altered dental hard tissues are reviewed, such as profilometry, microradiography, scanning electron microscopy, atom force microscopy, nano-and microhardness tests and iodide permeability test. Moreover, methods for chemical analysis of minerals dissolved from dental hard tissue are discussed. It becomes evident that the complex nature of erosive mineral loss and dissolution might not be comprehended by a single technique, but needs application of different approaches for full understanding. Copyright © 2006 S. Karger AG, Basel Acid attack leads to an irreversible loss of the outermost enamel and dentin layers and to partial demineralization (softening) of the tooth surface. In enamel, the thickness of the softened layer is estimated to be 2-5 tJm [1,2] [1, 2]. The softened eroded tooth surface is highly susceptible to abrasive wear, and mechanical impacts such as toothbrushing can easily remove the superficially demineralized dental hard tissue [3][4][5] [3][4][5]. For simulating intra-oral erosion as closely as possible, it is desirable to assess the erosive effects on native tooth surfaces. Most of the methods described below need polished surfaces for precise assessment of the erosively induced defects or for creating reference surfaces, which means that the natural, often fluoridated surface of the tooth has to be removed. However, it should be considered that in the case of intra-oral erosion the outermost surface layers are also continuously removed by the acid attack, so that a 'polished' surface is Attin 2 cre-ated. When monitoring of erosive surface alterations within a period of time is performed, it could become necessary to fix a specimen in the measuring device i...

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“…89 In vitro culture studies in bovine enamel have established the antierosion properties of nano HA when mixed with sports drinks. 90 Another in vitro study has proved the efficacy of nano carbonate apatite in preventing the restaining after the bleaching of the dental enamel. 91 There are clear reports on the antibacterial effects of silver nanoparticles and silver-impregnated nano BG in the prevention of caries.…”

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confidence: 99%

Regenerative nanomedicine: current perspectives and future directions

Chaudhury¹,

Kumar²,

Kandasamy³

et al. 2014

IJN

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Nanotechnology has considerably accelerated the growth of regenerative medicine in recent years. Application of nanotechnology in regenerative medicine has revolutionized the designing of grafts and scaffolds which has resulted in new grafts/scaffold systems having significantly enhanced cellular and tissue regenerative properties. Since the cell–cell and cell-matrix interaction in biological systems takes place at the nanoscale level, the application of nanotechnology gives an edge in modifying the cellular function and/or matrix function in a more desired way to mimic the native tissue/organ. In this review, we focus on the nanotechnology-based recent advances and trends in regenerative medicine and discussed under individual organ systems including bone, cartilage, nerve, skin, teeth, myocardium, liver and eye. Recent studies that are related to the design of various types of nanostructured scaffolds and incorporation of nanomaterials into the matrices are reported. We have also documented reports where these materials and matrices have been compared for their better biocompatibility and efficacy in supporting the damaged tissue. In addition to the recent developments, future directions and possible challenges in translating the findings from bench to bedside are outlined.

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The addition of nano-sized hydroxyapatite to a sports drink to inhibit dental erosion—In vitro study using bovine enamel

Cited by 61 publications

References 44 publications

Long-term protective effect of surface sealants against erosive wear by intrinsic and extrinsic acids

Long-term protective effect of surface sealants against erosive wear by intrinsic and extrinsic acids

Methods for Assessment of Dental Erosion

Regenerative nanomedicine: current perspectives and future directions

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