The action of sulphanilamide and its derivatives with special reference to tropical diseases

Buttle, G. A. H.

doi:10.1016/s0035-9203(39)90096-9

Cited by 5 publications

(2 citation statements)

References 51 publications

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“…The successful treatment of malaria with sulphanilamide compounds has been reported by several workers, but the results as a whole are, as Buttle (1939) pointed out, somewhat contradictory. Niven (1938) considered that though sulphanilamide had some action upon P. falciparum and P. vivax it was so slight that it was of academic interest only.…”

Section: Drugs Which Differ In Their Action Upon Malaria Of Man Monkmentioning

confidence: 94%

Chemotherapy and avian malaria

Bishop

1942

Parasitology

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Malaria is endemic over a wide area of the earth's surface. Although popularly associated with tropical or subtropical countries, it occurs as far north as the south of Sweden and Lake Ladoga in Russia and as far south as Bechuanaland, Swaziland and Natal in South Africa and the Argentine in South America. Though most frequent in low-lying districts it may be found at altitudes as great as 6000–9000 ft.

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Section: Drugs Which Differ In Their Action Upon Malaria Of Man Monkmentioning

confidence: 94%

Chemotherapy and avian malaria

Bishop

1942

Parasitology

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“…They have been in clinical use for over 60 years. Sulfanilamide was synthesized by Gelmo in 1908 and 1917 at the Rockefeller Institute this compound was added to quinine derivatives to increase bactericidal activity [19] and [20]. The discovery of Sulfanilamide introduces a new epoch in chemotherapy.…”

Section: 11-sulfonamidesmentioning

confidence: 99%

Previously licensed anti-mycobacterial drugs: a re-appraisal.

Muhammed¹

2016

JZS

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The discovery of antimycobacterial agent was the outcome of intensive efforts made between 1930 and 1970 to identify antimicrobial drugs. Sulfonamides (1930s), Streptomycin (1944) and Rifampicin (1965) are first and the last of the anti-mycobacterial drugs currently in use. Despite the availability of effective anti-tuberculosis chemotherapy, significant morbidity and mortality due to this disease continue to occur. The emergence and spread of multi-drug resistant (MDR) and extensively-drug resistant (XDR) strains of Mycobacterium tuberculosis has more complicated the problem of tuberculosis (TB) control and reduced the effectiveness of the current anti-TB drug. The present situation clearly demonstrates the need for a re-evaluation of our knowledge to treating TB and the current TB drugs. One of the highest achievements of modern medicine has been the development of antibiotics for the treatment of lethal infections. Unfortunately, the progress for new drugs against tuberculosis has been very inadequate over the past four decades. In the fight against emerging MDR and XDR resistance we can no longer rely completely on the finding of new antibiotics; we must also follow rational approaches to the use of older antibiotics such as sulfonamide. This review provides a concise historical of previously licensed drugs for treatment of tuberculosis and the targets and their mode of action of these drugs are briefly discussed.

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Bancroftian Filariasis and Elephantiasis

Shattuck

1943

Medical Clinics of North America

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The action of sulphanilamide and its derivatives with special reference to tropical diseases

Cited by 5 publications

References 51 publications

Chemotherapy and avian malaria

Chemotherapy and avian malaria

Previously licensed anti-mycobacterial drugs: a re-appraisal.

Bancroftian Filariasis and Elephantiasis

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