THE ACTION OF PHENANTHROLINE METAL CHELATES AND RELATED SUBSTANCES ON ERYSIPELOTHRIX RHUSIOPATHIAE AND FUSIFORMIS NODOSUS

Abstract

Summary Metal chelates, quaternary salts and hydrochlorides of 3,4,5,‐tetramethyl‐1,10‐phenanthroline are bactericidal to E. rhusiopathiae and F. nodosus; for the metal chelates, the rank order of speed of bactericidal action against E. rhusiopathiae is Cu(II) > Fe(Ii) = Ni(II) ≥ Ru(II) > Zn(II) > Mn(II) = Co(II). E. rhusiopathiae does not develop significant resistance to the Cu(II) chelate. The unusual susceptibility of F. nodosus to the Co(II) chelate and the possible uses of such metal chelates in veterinary practice are discussed.