The action of heavy metals on the gametes of the marine mussel, Mytilus edulis (L.)-II. Uptake of copper and zinc and their effect on respiration in the sperm and unfertilized egg

Akberali, Hassan B.; Earnshaw, M. J.; Marriott, K.R.M.

doi:10.1016/0141-1136(85)90019-4

Cited by 22 publications

(10 citation statements)

References 28 publications

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“…In a previous study, we illustrated that exposure to heavy metals can affect reproduction efficiency of aquatic biota and can lead to a gradual distinction of their generations in polluted waters (Ebrahimi 2004a). Low-level heavy metal pollution could impact reproduction either indirectly via accumulation in the reproductive organs or directly by acting on the free gametes (sperm or ovum) that are released into the water (Akberali et al 1985). Control of reproduction in fish is complex and is regulated by a wide range of factors; low-level pollution could affect any part of this pathway.…”

Section: Introductionmentioning

confidence: 99%

Concentration of four heavy metals (cadmium, lead, mercury, and arsenic) in organs of two cyprinid fish (Cyprinus carpio and Capoeta sp.) from the Kor River (Iran)

Ebrahimi

Taherianfard

2009

Environ Monit Assess

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Concentration of heavy metals in aquatic animals mainly occurs due to industrial contamination. In this study, the concentrations of four heavy metals (cadmium, lead, mercury, and arsenic) in organs of two cyprinid fish and in water collected from three sections of the Kor River, Iran were determined using the inductively coupled plasma method. Pathological and hormonal changes due to metal contamination were also measured. The concentrations of heavy metals in tissue of fish from the middle sampling zone were significantly higher (p < 0.05) than those from the other two sampling zones, whereas no significant differences (p > 0.05) were detected between the two sexes and species. High levels of metals were found in the ovaries and testes; estradiol in females and progesterone and testosterone in males from the middle study site were significantly (p < 0.05) lower than values from the other two sites. Pathological changes in blood cells, liver, and kidneys of fishes were significantly higher in highly polluted areas (middle sampling zone). These results show that industrial activities have polluted the river and that the maximum concentrations of Cd, Pb, and Hg were higher than the permissible levels for human consumption.

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Section: Introductionmentioning

confidence: 99%

Concentration of four heavy metals (cadmium, lead, mercury, and arsenic) in organs of two cyprinid fish (Cyprinus carpio and Capoeta sp.) from the Kor River (Iran)

Ebrahimi

Taherianfard

2009

Environ Monit Assess

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“…have been utilised in biological effects monitoring programmes to assess the effects of exposure to aquatic contaminants for many years (Bayne 1976, Goldberg et al 1978, Widdows & Donkin 1992, Granmo 1995, Salazar & Salazar 1995. Mussels are ubiquitous and are known to exhibit a range of biological responses when exposed to contaminants (Goldberg et al 1978, Rasmussen 1982, Calabrese et al 1984, Akberali et al 1985, O'Connor 1998, Widdows et al 2002. As such, mussels have been suggested as a sentinel for use in contaminant and biological effects monitoring programmes and offer considerable potential for comparison of international data on the health status of our seas and oceans.…”

Section: Introductionmentioning

confidence: 99%

Mussel histopathology: effects of season, disease and species

Bignell¹,

Dodge²,

Feist³

et al. 2008

Aquat. Biol.

100

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ABSTRACT:We assessed seasonal histological changes as markers of health status in mussels Mytilus spp. sampled from Southampton Water, Hampshire, UK and the River Exe, Devon, UK between November 2004 and October 2005. A total of 29 health parameters related to pathogens, inflammatory and non-specific pathologies, and reproductive and physiological condition were recorded monthly from individual mussels collected from these 2 sites. We then assessed the diffential prevalence of these health parameters according to species. M. edulis, M. galloprovincialis and their hybrids were identified using the Glu-5' gene and the ME15 and ME16 primer sets that distinguish alleles specific to M. edulis (180 bp), M. galloprovincialis (126 bp) and hybrids (180 bp/126 bp). Although no overall annual differences were observed between species with respect to median levels of adipogranular (ADG) tissue and reproductive status, specific differences in reproductive status were observed within individual months. During these months (August to October), M. edulis exhibited a relatively lower reproductive status compared to M. galloprovincialis and hybrids. With respect to all remaining health parameters (pathogens, inflammatory and non-specific pathology), principal components analysis revealed no overall differences between species throughout the year. However, greater differences were observed between species during the autumn and winter than during the spring and summer, thus indicating that species differences may be exacerbated by season. This study highlights how species can affect the accurate interpretation of histopathology data collected during biological effects monitoring programmes. Whether species can also affect the biomarker response of Mytilus mussels to contaminated environments remains to be shown. The results are discussed in the context of biological effects monitoring utilising mussels.

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“…If Zn 2+ is added to the fertilization environment, the loss of Zn 2+ due to dilution may be hindered by the exogenous Zn 2+ in the surrounding medium, which may exist at a higher concentration. Evidence suggests that Zn 2+ has the ability to penetrate the sperm membrane [9,27]; therefore, extracellular Zn 2+ passing through the sperm membrane may become a constituent in the cytoplasm. The ability of Zn 2+ to also pass through the mitochondrial membrane is evident from previous work by Earnshaw et al [25] and Akberali et al [9].…”

Section: Discussionmentioning

confidence: 99%

“…The Zn 2+ was chosen because it is naturally found in the semen of many species, such as bulls and boars [7], as well as humans [8]. It has been suggested that Zn 2+ inhibits cellular respiration in the sperm cell, resulting in a cessation of sperm motility [9]. Therefore, Zn 2+ , as a contaminant introduced into the fertilization environment, may have significant inhibitory effects on sperm motility in amphibians.…”

Section: Introductionmentioning

confidence: 99%

Validation of an amphibian sperm inhibition toxicological test method using zinc

Christensen

Bishop²,

Richardson

et al. 2004

Enviro Toxic and Chemistry

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Analysis of sperm has been investigated as a possible method to examine the toxicity of environmental contaminants. The amphibian sperm inhibition toxicological test (ASITT) method examines the effects of contaminants on Xenopus laevis (African clawed frog) sperm motility and path trajectories. As part of a preliminary validation of the method, the effects of increasing divalent metal ion, zinc (Zn2+), on X. laevis sperm motility were examined. We hypothesized that Zn2+ concentration would have significant inhibitory effects on percent sperm motility, velocities, and trajectories. The Zn2+ was added to a control solution in concentrations from 0 to 1,417 microg/L. Sperm cells were videotaped at 30 frames per second under x 400 microscope, and percent motility was recorded and paths were mapped by marking the change in position of the sperm head over a period of 1 s. Sperm motility was categorized as progressive, hyperactivated, idle, or nonmotile, and velocities and trajectories were calculated on the basis of x,y coordinates. Increasing Zn2+ concentrations caused a significant exponential decay in percent total motility and progressive motility. Straight-line velocity increased with increasing Zn2+ concentrations. Overall, results suggest that Zn2+ may be interfering with cellular processes, such as cellular respiration, flagellar bending, or ion exchange, thereby inhibiting sperm motility.

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The action of heavy metals on the gametes of the marine mussel, Mytilus edulis (L.)-II. Uptake of copper and zinc and their effect on respiration in the sperm and unfertilized egg

Cited by 22 publications

References 28 publications

Concentration of four heavy metals (cadmium, lead, mercury, and arsenic) in organs of two cyprinid fish (Cyprinus carpio and Capoeta sp.) from the Kor River (Iran)

Concentration of four heavy metals (cadmium, lead, mercury, and arsenic) in organs of two cyprinid fish (Cyprinus carpio and Capoeta sp.) from the Kor River (Iran)

Mussel histopathology: effects of season, disease and species

Validation of an amphibian sperm inhibition toxicological test method using zinc

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