The accuracy of symptom‐based definition of chronic rhinosinusitis

Tahamiler, Rauf; Çanakçıoğlu, Salih; Öğreden, Şahin; Acıoğlu, Engin

doi:10.1111/j.1398-9995.2007.01397.x

Cited by 36 publications

(28 citation statements)

References 15 publications

(16 reference statements)

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“…The same symptom structure was reported by Montnémery and colleagues, 9 although assessed by different methods. A strong positive correlation between SNAQ-11 scores and endoscopic scores was found in our study and is in opposition to the results of Tahamiler and colleagues, 21 who found that 75% of patients with symptom-based diagnosis of chronic nonallergic rhino-sinusitis had no endoscopic pathology. Similar doubts on the value of symptom-based diagnosis of chronic rhinosinusitis have been raised by others.…”

Section: Discussioncontrasting

confidence: 99%

Rhinosinusitis in COPD: symptoms, mucosal changes, nasal lavage cells and eicosanoids

Piotrowska

Piotrowski²,

Kurmanowska³

et al. 2010

COPD

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Abstract:The coexistence of upper airways disease with chronic obstructive pulmonary disease (COPD) is not well documented. The aim of this research was to assess sino-nasal inflammation in COPD by various tools, and look for the impact on quality of life, relation to smoking, disease severity and systemic inflammation. Current and ex-smokers with COPD (n = 42) and healthy never-smokers (n = 21) were included in this study. COPD severity was assessed by GOLD criteria and BODE index. Markers of systemic inflammation were measured. Nasal symptoms and general quality of life were assessed using the questionnaires; sino-nasal questionnaire (SNAQ-11) and St. George's Respiratory Questionnaire (SGRQ). Nasal endoscopy and saccharine test were performed. Nasal lavages were collected for cytological examination and eicosanoids (cysteinyl leukotrienes, leukotriene B4, 8-isoprostane). Symptoms and endoscopic scores were higher in COPD (P  0.0001). Only SGRQ symptoms subscore correlated with SNAQ-11 (r = 0.34, P = 0.035). Mucociliary clearance was impaired only in current smokers (9.91 ± 0.49 versus 13.12 ± 0.68 minutes, P  0.001). 8-isoprostane was higher in COPD smokers compared to the controls (0.17 ± 0.04 versus 0.34 ± 0.09 pg/g protein, P  0.05). Endoscopic score and mucociliary of impairment patients who currently smoked cigarettes correlated with concentrations of 8-isoprostane. None of the parameters correlated with disease severity and markers of systemic inflammation. We provide evidence of upper airways disease in COPD, which appears to be related more to patients who currently smoke than to disease severity.

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Section: Discussioncontrasting

confidence: 99%

Rhinosinusitis in COPD: symptoms, mucosal changes, nasal lavage cells and eicosanoids

Piotrowska

Piotrowski²,

Kurmanowska³

et al. 2010

COPD

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“…Furthermore, the entity is rarely discussed in pediatric medicine, although upper respiratory complaints are common. The diagnosis of chronic rhinosinusitis cannot be made on the grounds of symptoms only (22). Epidemiologic data based on questionnaires for chronic rhinosinusitis are therefore limited and difficult to assess.…”

Section: Magnitude Of the Problemmentioning

confidence: 99%

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper

Bousquet

Fokkens

Burney

et al. 2008

Allergy

163

148

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Important research questions in allergy and related diseases: nonallergic rhinitis: a GA 2 LEN paper Nonallergic rhinitis (NAR) can be defined as a chronic nasal inflammation which is not caused by systemic IgE-dependent mechanisms. It is common and probably affects far more than 200 million people worldwide. Both children and adults are affected. However, its exact prevalence is unknown and its phenotypes need to be evaluated using appropriate methods to better understand its pathophysiology, diagnosis and management. It is important to differentiate between infectious rhinitis, allergic/NAR and chronic rhinosinusitis, as management differs for each of these cases. Characterization of the phenotype, mechanisms and management of NAR represents one of the major unmet needs in allergic and nonallergic diseases. Studies on children and adults are required in order to appreciate the prevalence, phenotype, severity and co-morbidities of NAR. These studies should compare allergic and NAR and consider different age group populations including elderly subjects. Mechanistic studies should be carried out to better understand the disease(s) and risk factors and to guide towards an improved diagnosis and therapy. These studies need to take the heterogeneity of NAR into account. It is likely that neuronal mechanisms, T cells, innate immunity and possibly auto-immune responses all play a role in NAR and may also contribute to the symptoms of allergic rhinitis.

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“…Although CRS is not a lifethreatening disease, it can significantly decrease patientÕs QoL (8)(9)(10). Quality of life is a very important outcome in the evaluation of CRS severity and its measurements reflect the effect that symptoms and disease have on the patientÕs daily life (11). However, it is of interest that the presence and/or severity of nasal symptoms do not always correlate with QoL questionnaires (12).…”

mentioning

confidence: 99%

Chronic rhinosinusitis and nasal polyps: the role of generic and specific questionnaires on assessing its impact on patient’s quality of life

Alobid

Bernal‐Sprekelsen

Mullol

2008

Allergy

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Chronic rhinosinusitis (CRS) including nasal polyps is a chronic inflammatory disease of the nasal and paranasal sinus mucosa that, despite differing hypotheses of its cause, remains poorly understood. Primary symptoms are nasal blockage, loss of smell, rhinorrhea, and facial pain or pressure. Chronic rhinosinusitis causes significant physical symptoms, has a negative impact on quality of life (QoL), and can substantially impair daily functioning. A global evaluation of patients must include, together with nasal symptoms, nasal endoscopy, and CT scan, the measurement of QoL. To assess QoL in CRS, specific and generic questionnaires may be used. Chronic rhinosinusitis has a considerable impact on a patient’s QoL but comorbidities, such as asthma and atopy, have an accumulative negative effect. Both medical and surgical treatments lead to a similar improvement on the QoL of CRS and nasal polyp patients.

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The accuracy of symptom‐based definition of chronic rhinosinusitis

Cited by 36 publications

References 15 publications

Rhinosinusitis in COPD: symptoms, mucosal changes, nasal lavage cells and eicosanoids

Rhinosinusitis in COPD: symptoms, mucosal changes, nasal lavage cells and eicosanoids

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper

Chronic rhinosinusitis and nasal polyps: the role of generic and specific questionnaires on assessing its impact on patient’s quality of life

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The accuracy of symptom‐based definition of chronic rhinosinusitis

Cited by 36 publications

References 15 publications

Rhinosinusitis in COPD: symptoms, mucosal changes, nasal lavage cells and eicosanoids

Rhinosinusitis in COPD: symptoms, mucosal changes, nasal lavage cells and eicosanoids

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper

Chronic rhinosinusitis and nasal polyps: the role of generic and specific questionnaires on assessing its impact on patient’s quality of life

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Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper