The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia

Dijkhuizen, F. P. H. L. J.; Mol, Ben Willem J.; Brölmann, Hans A.M.; Heintz, A. Peter M.

doi:10.1002/1097-0142(20001015)89:8<1765::aid-cncr17>3.3.co;2-6

Cited by 117 publications

(148 citation statements)

References 21 publications

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“…4 Although some authors recommend hysteroscopy-guided biopsy in the diagnostic evaluation for endometrial cancer, Pipelle-guided biopsy and D&C have also demonstrated an acceptable diagnostic accuracy. 5,6 Attending to international recommendations, 3 the indication of regional lymphadenectomy in endometrial cancer is determined by several features including tumor grade differentiation. The latter helps to tailor an adequate surgical plan as well as to provide precise preoperative information for patients.…”

mentioning

confidence: 99%

Tumor Grade Correlation Between Preoperative Biopsy and Final Surgical Specimen in Endometrial Cancer: The Use of Different Diagnostic Methods and Analysis of Associated Factors

Lago¹,

Martín

Ballesteros

et al. 2018

Int J Gynecol Cancer

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Preoperative biopsy, regardless of the method, has its limitations in predicting the tumor grade compared with final surgical specimen in women with endometrioid endometrial cancer at an apparent early stage. Concordance between the biopsy and hysterectomy specimen is less likely to happen in the case of preoperative G1 or G2 tumors, as well as in big tumors. Although hysteroscopy was associated with the highest tumor grade agreement, no differences in correlation between the 3 methods (D&C, Pipelle, and hysteroscopy) were found.

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mentioning

confidence: 99%

Tumor Grade Correlation Between Preoperative Biopsy and Final Surgical Specimen in Endometrial Cancer: The Use of Different Diagnostic Methods and Analysis of Associated Factors

Lago¹,

Martín

Ballesteros

et al. 2018

Int J Gynecol Cancer

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“…Endometrium sampling for detection of endometrial cancer has a sensitivity of 95% and a specificity of 99%, while in cases of atypical hyperplasia these values are 88% and 98%, respectively. Hysteroscopy is therefore superior compared to other endometrial sampling or evaluation techniques (43). Previous reports have demonstrated a high incidence of insufficient endometrial sampling in postmenopausal women (44).…”

Section: Discussionmentioning

confidence: 99%

The contribution of hysteroscopy to the detection malignancy in symptomatic postmenopausal women

Liberis

Tsikouras

Zografou

et al. 2010

Minimally Invasive Therapy & Allied Technologies

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Hysteroscopic evaluation of endometrial cavity is widely used in cases of abnormal uterine bleeding. The aim of the present study is to compare the hysteroscopic and histological findings in women suffering from postmenopausal bleeding. Between 1990 and 2009, 425 women aged 47-83 years were included in the study. None of the women had received hormonal therapy or had any malignancy in the past. All women underwent diagnostic hysteroscopy and histologic sampling of the endometrial cavity. Hysteroscopy was successfully completed in 423 women and was suggestive of malignant lesions in 23 cases, which were confirmed histologically. The hysteroscopic findings in three cases were suggestive of atrophic endometrium, atypical hyperplasia and endometrial carcinoma, and the histologic diagnosis confirmed endometrial carcinoma (two cases) and one uterine sarcoma. Hysteroscopy proves to be a safe and effective technique in the diagnosis and management of abnormal uterine bleeding.

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“…The diagnosis of endometrial cancer is made reliably based on histologic and radiologic evaluation. Endometrial biopsy has high sensitivity for a diagnosis of endometrial carcinoma 23,24 ; however, very few studies have reported its sensitivity in diagnosis of mesenchymal tumors and are limited to small single-institution reports. 11,25 Because of the distribution of sarcomas within the myometrium, the reported sensitivities of 33–67%are not surprising.…”

Section: Accuracy Of Clinical and Radiographic Predictors Of Malignancymentioning

confidence: 99%

A critical assessment of morcellation and its impact on gynecologic surgery and the limitations of the existing literature

Liu

Galvan-Turner

Pfaendler

et al. 2015

American Journal of Obstetrics and Gynecology

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Uterine sarcomas are rare uterine malignancies that are difficult to diagnose preoperatively. Because of cases of disseminated sarcoma after laparoscopic hysterectomy, the role of power morcellators in gynecologic surgery has been questioned. Morcellation is an integral part of making laparoscopic surgery possible for the removal of large uterine leiomyomata, and the development of power morcellation has increased efficiency during these procedures. Minimally invasive surgery has demonstrated benefits that include improved pain control, decreased infection risk, and faster surgical recovery and return to work. In this review, we examine the risk of incidental sarcoma at the time of surgery, the quality of the data, the accuracy of clinical and radiologic predictors of uterine sarcoma, and the impact of morcellation on the prognosis of uterine sarcoma.

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The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia

Cited by 117 publications

References 21 publications

Tumor Grade Correlation Between Preoperative Biopsy and Final Surgical Specimen in Endometrial Cancer: The Use of Different Diagnostic Methods and Analysis of Associated Factors

Tumor Grade Correlation Between Preoperative Biopsy and Final Surgical Specimen in Endometrial Cancer: The Use of Different Diagnostic Methods and Analysis of Associated Factors

The contribution of hysteroscopy to the detection malignancy in symptomatic postmenopausal women

A critical assessment of morcellation and its impact on gynecologic surgery and the limitations of the existing literature

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