The accuracy and precision of two non-invasive, magnetic resonance-guided focused ultrasound-based thermal diffusivity estimation methods

Dillon, Christopher; Payne, Allison; Christensen, Douglas A.; Roemer, R. B.

doi:10.3109/02656736.2014.945497

Cited by 15 publications

(28 citation statements)

References 27 publications

(35 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the past, applying (1) for analytical estimation of ultrasound and thermal properties has required eliminating the time integral through the assumption of instantaneous heating (Parker 1983, Cheng and Plewes 2002, Anand and Kaczkowski 2008, 2009, Dragonu et al 2009, Cornelis et al 2011, Zhang et al 2013, 2015) or simplifying the integrand for evaluation by neglecting perfusion (Cline et al 1994, Dillon et al 2012, 2013, 2014) and/or utilizing only the center-line, on-axis solution (Parker 1985, Kress and Roemer 1987, Cline et al 1994, Dillon et al 2012). To our knowledge, the full analytical solution of (1) cannot be directly evaluated.…”

Section: Theorymentioning

confidence: 99%

“…The desired cooling solutions are obtained by the superposition of heating solutions according to (Cline et al 1994, Dillon et al 2014)…”

Section: Theorymentioning

confidence: 99%

“…In recent years, MRTI has been used in estimation techniques for determining a variety of ultrasound (Salomir et al 2000, Dragonu et al 2009, Dillon et al 2012, 2013, Appanaboyina et al 2013, Alon et al 2013), thermal (Cline et al 1994, Salomir et al 2000, Cheng and Plewes 2002, Huttunen et al 2006, Sumi and Yanagimura 2007, Dragonu et al 2009, Cornelis et al 2011, Zhang et al 2013, Appanaboyina et al 2013, Alon et al 2013, Dillon et al 2013, 2014, Zhang et al 2013, 2015), and perfusion properties (Cheng and Plewes 2002, Huttunen et al 2006, Dragonu et al 2009, Cornelis et al 2011, Appanaboyina et al 2013, Alon et al 2013, Dillon et al 2015). …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Analytical estimation of ultrasound properties, thermal diffusivity, and perfusion using magnetic resonance-guided focused ultrasound temperature data

2016

View full text Add to dashboard Cite

For thermal modeling to play a significant role in treatment planning, monitoring, and control of magnetic resonance-guided focused ultrasound (MRgFUS) thermal therapies, accurate knowledge of ultrasound and thermal properties is essential. This study develops a new analytical solution for the temperature change observed in MRgFUS which can be used with experimental MR temperature data to provide estimates of the ultrasound initial heating rate, Gaussian beam variance, tissue thermal diffusivity, and Pennes perfusion parameter. Simulations demonstrate that this technique provides accurate and robust property estimates that are independent of the beam size, thermal diffusivity, and perfusion levels in the presence of realistic MR noise. The technique is also demonstrated in vivo using MRgFUS heating data in rabbit back muscle. Errors in property estimates are kept less than 5% by applying a third order Taylor series approximation of the perfusion term and ensuring the ratio of the fitting time (the duration of experimental data utilized for optimization) to the perfusion time constant remains less than one.

show abstract

Section: Theorymentioning

confidence: 99%

“…The desired cooling solutions are obtained by the superposition of heating solutions according to (Cline et al 1994, Dillon et al 2014)…”

Section: Theorymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Analytical estimation of ultrasound properties, thermal diffusivity, and perfusion using magnetic resonance-guided focused ultrasound temperature data

2016

View full text Add to dashboard Cite

show abstract

“…Another study evaluated the accuracy and precision of two noninvasive thermal diffusivity estimation methods, 68 and MR acoustic radiation force imaging, in order to propose an elegant adjunct to MRgFUS for treatment planning and optimization, permitting in situ assessment of the focusing and targeting quality. 69 Even real-time methods are being developed for motion-compensated MRI thermometry in MRgHIFU treatment of abdominal organs, which may be considered in the treatment of the chest wall.…”

Section: Focused Ultrasound Mri and Musculoskeletal Tissues: Pros Anmentioning

confidence: 99%

MRI-guided focused ultrasound surgery in musculoskeletal diseases: the hot topics

Bazzocchi¹,

Napoli²,

Sacconi³

et al. 2016

BJR

View full text Add to dashboard Cite

MRI-guided focused ultrasound surgery (MRgFUS) is a minimally invasive treatment guided by the most sophisticated imaging tool available in today's clinical practice. Both the imaging and therapeutic sides of the equipment are based on non-ionizing energy. This technique is a very promising option as potential treatment for several pathologies, including musculoskeletal (MSK) disorders. Apart from clinical applications, MRgFUS technology is the result of long, heavy and cumulative efforts exploring the effects of ultrasound on biological tissues and function, the generation of focused ultrasound and treatment monitoring by MRI. The aim of this article is to give an updated overview on a "new" interventional technique and on its applications for MSK and allied sciences

show abstract

“…Thermal simulations were performed for both the corrected and uncorrected pressure patterns using a finite-difference implementation 30 of the Pennes bioheat equation,…”

Section: I Thermal Simulationsmentioning

confidence: 99%

Phase aberration simulation study of MRgFUS breast treatments

et al. 2016

Self Cite

View full text Add to dashboard Cite

Purpose: This simulation study evaluates the effects of phase aberration in breast MR-guided focused ultrasound (MRgFUS) ablation treatments performed with a phased-array transducer positioned laterally to the breast. A quantification of these effects in terms of thermal dose delivery and the potential benefits of phase correction is demonstrated in four heterogeneous breast numerical models. Methods: To evaluate the effects of varying breast tissue properties on the quality of the focus, four female volunteers with confirmed benign fibroadenomas were imaged using 3T MRI. These images were segmented into numerical models with six tissue types, with each tissue type assigned standard acoustic properties from the literature. Simulations for a single-plane 16-point raster-scan treatment trajectory centered in a fibroadenoma in each modeled breast were performed for a breast-specific MRgFUS system. At each of the 16 points, pressure patterns both with and without applying a phase correction technique were determined with the hybrid-angular spectrum method. Corrected phase patterns were obtained using a simulation-based phase aberration correction technique to adjust each element's transmit phase to obtain maximized constructive interference at the desired focus. Thermal simulations were performed for both the corrected and uncorrected pressure patterns using a finite-difference implementation of the Pennes bioheat equation. The effect of phase correction was evaluated through comparison of thermal dose accumulation both within and outside a defined treatment volume. Treatment results using corrected and uncorrected phase aberration simulations were compared by evaluating the power required to achieve a 20• C temperature rise at the first treatment location. The extent of the volumes that received a minimum thermal dose of 240 CEM at 43• C inside the intended treatment volume as well as the volume in the remaining breast tissues was also evaluated in the form of a dose volume ratio (DVR), a DVR percent change between corrected and uncorrected phases, and an additional metric that measured phase spread. Results: With phase aberration correction applied, there was an improvement in the focus for all breast anatomies as quantified by a reduction in power required (13%-102%) to reach 20• C when compared to uncorrected simulations. Also, the DVR percent change increased by 5%-77% in seven out of eight cases, indicating an improvement to the treatment as measured by a reduction in thermal dose deposited to the nontreatment tissues. Breast compositions with a higher degree of heterogeneity along the ultrasound beam path showed greater reductions in thermal dose delivered outside of the treatment volume with correction applied than beam trajectories that propagated through more homogeneous breast compositions. An increasing linear trend was observed between the DVR percent change and the phase-spread metric (R 2 = 0.68). Conclusions: These results indicate that performing phase aberration correction for breast MRgFUS treatme...

show abstract

The accuracy and precision of two non-invasive, magnetic resonance-guided focused ultrasound-based thermal diffusivity estimation methods

Cited by 15 publications

References 27 publications

Analytical estimation of ultrasound properties, thermal diffusivity, and perfusion using magnetic resonance-guided focused ultrasound temperature data

Analytical estimation of ultrasound properties, thermal diffusivity, and perfusion using magnetic resonance-guided focused ultrasound temperature data

MRI-guided focused ultrasound surgery in musculoskeletal diseases: the hot topics

Phase aberration simulation study of MRgFUS breast treatments

Contact Info

Product

Resources

About