The Abuse of Prescription Medications: Borderline Personality Patients in Psychiatric versus Non-Psychiatric Settings

Sansone, Randy A.; Wiederman, Michael W.

doi:10.2190/pm.39.2.c

Cited by 18 publications

(9 citation statements)

References 29 publications

(39 reference statements)

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“…These findings corroborate previous literature indicating that poor psychological health is associated with drug OD (Bohnert et al, 2012; Toblin et al, 2010; Tobin and Latkin, 2003; Burns et al, 2004). People with higher levels of psychological distress, particularly those who have been treated in psychiatric institutions, may be inclined to take more of their medications than prescribed in an effort to reduce distress, or take their medications in combination with other drugs or alcohol (Farrell et al, 1996; Robinson et al, 2011; Sansone and Wiederman, 2009). More research is needed to better understand the role of psychological distress, psychiatric care, and prescribing patterns of tranquilizer medications in overdose risk.…”

Section: Discussionmentioning

confidence: 99%

Factors associated with history of non-fatal overdose among young nonmedical users of prescription drugs

Silva

Schrager

Kecojevic

et al. 2013

Drug and Alcohol Dependence

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Objectives The current study examines the prevalence and correlates of lifetime non-fatal overdose (OD) involving the nonmedical use of prescription opioids and tranquilizers among a sample of high-risk young adults in New York, NY and Los Angeles, CA. Methods Data were derived from a cross-sectional study of 16–25 year old nonmedical users of prescription drugs (n = 596). Unadjusted associations between OD history and socio-demographic and drug use variables were investigated in bivariate logistic regression models. Multivariate logistic regression models identified correlates of non-fatal OD. Results Lifetime prevalence of non-fatal overdose involving prescription opioids and/or tranquilizers was 23.6%. Factors associated with increased risk of non-fatal overdose included lower social class while growing up (OR: 1.81, 95% CI: [1.15, 2.83], p < 0.01), having ever received care at a psychiatric hospital (OR: 1.79,95% CI: [1.12,2.85], p <0.05), ever witnessing a family member OD on drugs (OR: 1.59,95% CI: [1.02,2.50], p < 0.05), being prescribed tranquilizers (OR: 2.07,95% CI: [1.29,4.27], p < 0.01), ever snorting or sniffing opioids (OR: 2.51,95% CI: [1.48,4.27], p < 0.001), injecting tranquilizers (OR: 3.09,95% CI: [1.61, 5.93],p< 0.001), and past 90-day injection drug use (OR: 1.68, 95% CI: [1.03, 2.74], p < 0.05). Participants who reported past 90-day stimulant misuse had lower odds of reporting OD compared to those who were not recent stimulant users (OR: 0.60,95% CI: [0.38–0.96], p < 0.05). Conclusions This study documents the high prevalence of experiencing non-fatal overdose among young nonmedical users of prescription drugs. Results could inform overdose prevention efforts throughout the U.S.

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Section: Discussionmentioning

confidence: 99%

Factors associated with history of non-fatal overdose among young nonmedical users of prescription drugs

Silva

Schrager

Kecojevic

et al. 2013

Drug and Alcohol Dependence

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“…Indeed, BPD is the most frequently diagnosed personality disorder (PD) in psychiatric facilities (Zimmerman, Rothschild, & Chelminski, 2005). BPD is often characterized by self-harm behavior (Herpertz, 1995;Schaffer, Carroll, & Abramowitz, 1982;Simeon et al, 1992;Walsh & Rosen, 1998), internalizing psychopathology symptoms (Deltito et al, 2001;McGlashen et al, 2000;Zanarini et al, 2004), promiscuous sexual behavior (Hull, Clarkin, & Yeomans, 1993;Sansone & Wiederman, 2009), aggression (Newhill, Eack, & Mulvey, 2009, 2012, and substance abuse (Johnson et al, 2003;Tadic et al, 2009;Zanarini et al, 1998;Zlotnick, Rothschild, & Zimmerman, 2002). In addition to these behaviors, BPD has historically been associated with a history of abuse and/or neglect (Ball & Links, 2009;Beauchaine et al, 2009;Bornovalova et al, 2006;Carlson, Egeland, & Sroufe, 2009;Trull, 2001;Widom, Czaja, & Paris, 2009).…”

mentioning

confidence: 99%

Comparing External Correlates ofDSM-5Section II and Section III Dimensional Trait Operationalizations of Borderline Personality Disorder

Anderson

Sellbom

Sansone

et al. 2016

Journal of Personality Disorders

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The current study evaluated the relative associations of the DSM-5 Section II operationalization of Borderline Personality Disorder (BPD) and dimensional traits included in a diagnosis of BPD in DSM-5 Section III with conceptually relevant external criterion variables. It is important to determine whether or not Section II BPD and constellation of Section III BPD traits have similar positions in the nomological network representing the BPD construct. Moreover, it is important to determine whether or not the trait-based Section III BPD diagnosis is an improvement upon the categorical Section II diagnosis in regard to its associations with external criteria. To evaluate this, we used two samples, a patient sample consisting of 145 psychiatric patients and a university sample consisting of 399 undergraduate students. We conducted a series of correlation and regression analyses in order to determine the relative associations of these two diagnostic methodologies with relevant external criteria. Correlation analyses did not favor either model, but indicated that both Section II and Section III BPD have associations with external criterion variables relevant to BPD. The regression analyses tended to favor the trait-based Section III model, supporting the construct validity and use of the trait profile for BPD in DSM-5 Section III. Generally, it was concluded that the Section II and Section III operationalizations have similar positions in a nomological network representing the BPD construct.Borderline Personality Disorder (BPD) is a serious personality dysfunction characterized by symptoms such as affective instability, difficulties in interpersonal relationships, impulsivity, fear of abandonment, identity confusion, and risk for suicidal behaviors (American Psychiatric Association [APA], 2013). Prevalence rates for this disorder are high and estimated to be between 2-6% in the general population, 10% in outpatient mental health settings, and

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“…Indeed, a BPD diagnosis includes a pattern of maladaptive thoughts and behaviors such as aggression, risky sexual behaviors, self-harm, and dissociative experiences; it frequently co-occurs with other forms of psychopathology such as depression, anxiety, and posttraumatic stress disorder (PTSD; e.g., Ball & Links, 2009;McGlashan et al, 2000;Sansone & Sansone, 2011, 2012Sansone & Wiederman, 2009;Walsh & Rosen, 1998;Widom, Czaja, & Paris, 2009). BPD is particularly comorbid with symptoms of depression (Deltito et al, 2001;McGlashan et al, 2000;Zanarini, Frankenburg, Vujanovic, et al, 2004) and PTSD (Golier et al, 2003;Yen et al, 2002).…”

mentioning

confidence: 99%

“…Impulsivity and self-harm are components of BPD symptoms, and research has supported the associations between BPD diagnoses and various forms of externalizing psychopathology. For example, individuals with BPD are more likely to report casual sexual relationships and promiscuous sexual behavior than individuals without symptoms of BPD (Hull, Clarkin, & Yeomans, 1993;Sansone & Wiederman, 2009). In addition, selfharm, one of the most frequent behaviors observed in individuals with BPD, has been shown in numerous studies to have links with BPD symptoms (Herpertz, 1995;Schaffer, Carroll, & Abramowitz, 1982;Simeon, Stanley, & Frances, 1992;Walsh & Rosen, 1998).…”

mentioning

confidence: 99%

Construct Validity of theDSM–5Section III Personality Trait Profile for Borderline Personality Disorder

Anderson

Sellbom

2015

Journal of Personality Assessment

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This study evaluated the nomological network of the borderline personality disorder (BPD) trait profile in the Diagnostic and Statistical Manual of Mental Disorders (5th ed. [DSM-5]) Section III. BPD symptoms include a variety of maladaptive thoughts and behaviors, and it is important to determine if the Section III trait operationalization for BPD captures these behavioral symptoms, as well as shows similar associations as the traditional Section II version with external criteria. For this purpose, we used a sample of 285 undergraduate students and conducted correlation and regression analyses to delineate the associations between Section III BPD traits and conceptually relevant external criteria. A Section III Total score was meaningfully associated with all criteria. Moreover, externalizing psychopathology tended to be most highly associated with disinhibitory Section III BPD traits, whereas internalizing psychopathology tended to have its strongest unique associations with traits reflective of negative affectivity. These results provide support for the construct validity of the trait profile for BPD in DSM-5 Section III.

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The Abuse of Prescription Medications: Borderline Personality Patients in Psychiatric versus Non-Psychiatric Settings

Abstract: Regardless of setting, patients with BPD are at great risk for the abuse of prescription medications.

Cited by 18 publications

References 29 publications

Factors associated with history of non-fatal overdose among young nonmedical users of prescription drugs

Factors associated with history of non-fatal overdose among young nonmedical users of prescription drugs

Comparing External Correlates ofDSM-5Section II and Section III Dimensional Trait Operationalizations of Borderline Personality Disorder

Construct Validity of theDSM–5Section III Personality Trait Profile for Borderline Personality Disorder

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