The absence of the RecN protein suppresses the cellular defects of Deinococcus radiodurans irradiated cells devoid of the PprA protein by limiting recombinational repair of DNA lesions

Ultraviolet-B Radiation Stress-Induced Toxicity and Alterations in Proteome of <b><i>Deinococcus radiodurans</i></b>

“…D. radiodurans is known to be the most radiation-resistant bacterium and can tolerate other oxidative stresses [Cox and Battista, 2005]. Such remarkable stress tolerance has been attributed to its highly efficient DNA repair system, pres- ence of UV absorbing carotenoid pigment, and a strong protein protection system [Tian et al, 2007;Devigne et al, 2019]. In general, differential tolerance to UV radiation among bacteria could be due to the differences in the level of various defense mechanisms including the presence of certain photoprotective compounds [Battista, 1997;Slade and Radman, 2011].…”

“…These photoproducts alter the DNA conformation, which in turn inhibits replication and transcription leading to cell death [Rastogi et al, 2010;Santos et al, 2012;Chudobova et al, 2015]. However, unlike several other bacteria, Deinococcus radiodurans can survive and grow under very high doses of ionizing radiation as well as other abiotic stresses due to the presence of very efficient and unique DNA repair mechanisms, which allows them to repair both single-and double-stranded DNA breaks [Cox et al, 2010;Devigne et al, 2019].…”

Tuning Microbial Activity via Programmatic Alteration of Cell/Substrate Interfaces

“…[93] Apart from that, stimulations (such as electro, radio, and magnetic) applied to the substrate material (or provided by it) can serve as factors influencing the properties of cells or biofilms. [105][106][107][108] Furthermore, the reaction of a single cell may be different from a reaction of a resilient biofilm due to group sensing and stress response mechanisms typically developed in such communities. Additionally, the responses Figure 3.…”

“…[132] Other examples that can be found in the table include such bacteria as the gram negative mineralizing bacteria Shewanella putrefaciens (S. putrefaciens), [98] the skin microbiome gram positive bacterium Micrococcus lylae (M. lylae), [144] the industrially relevant gram negative bacterium, Streptomyces avidinii (S. avidinii), [147] the large gram positive soil bacterium, Bacillus megaterium (B. megaterium), [138] and the extremophile, radiation resistant gram-positive bacterium, Deinococcus radiodurans (D. radiodurans). [105,106] Eukaryotic fungal microbes included in these studies were the agriculturally important "black mold" filamentous fungus Aspergillus niger fungi (A. niger) [95] and the fermentation industry cellular yeast, Saccharomyces cerevisiae (S. cerevisiae). [94] This range of microbes represents not only a diversity of species and genomes but also other cellular properties such as the composition and mechanical properties of the cell wall.…”

“…As with the physiological examination of microbial interfacial reactions, genetic responses, target microorganisms are either grown in a liquid media (nutrient broth) and incubated in cell culture tubes, flasks or culturing chambers, [198,199,208,[200][201][202][203][204][205][206][207] or grown in Petri dishes on solid nutrient media like agar. [106,107,[209][210][211][212][213] Given the sensitivity of genetic stress responses, the diversity of these culturing conditions could be a cause for concern for consistency. Based on our literature analysis, relatively small amount of published papers have examined the microbial response to metallic, semiconducting or polymeric substrates and in many cases, cells do not interact with inorganic materials at all, since external stresses may be represented by temperature, pH changes or .…”