The ability of yoghurt supplemented with dietary fibers or brans extracted from wheat or rice to reduce serum lipids and enhance liver function in male hypercholesterolemic rats

Abstract

This study was undertaken to evaluate the effect of yoghurt supplementation with rice and wheat brans or dietary fibers on serum lipid profile, liver, and heart functionalities, and hepatopathological aspects of the liver of hypercholesterolemic rats. 48 male rats were divided into 8 groups. Group 1 was kept as negative control and fed with a standard diet, and groups 2 to 6 were fed a hypercholesterolemia‐induced diet supplemented with brans or dietary fibers of both grains. G2 received yoghurt without supplementation. The experiment lasted for 4 weeks. Results revealed that hypercholesterolemic rats administrated yoghurt supplemented with brans or dietary fibers reduced serum glucose from 113.9 ± 2.72 to 85.5 ± 4.94 in the serum of animals that received dietary fibers of rice and wheat, respectively. In addition, lipids profile and liver antioxidant status were improved. In addition, liver and heart functionalities and liver histopathological architecture were all improved depending on the type of administrated brans or fibers added to yoghurt. The inclusion of 0.5% of rice or wheat brans could be recommended to be added to yoghurt. Practical applications Yoghurt is the most famous fermented milk in the world. Supplementation of yoghurt with rice and wheat brans or dietary fibers increased its nutritional value. We proved that this new product contributes to reducing serum glucose, improving lipids profile, and enhancing liver and heart functions in hypercholesterolemic rats. This study confirmed the suitability to add a thesis type of brans or dietary fibers as bioactive ingredients to yoghurt and increased the varieties of functional foods.

Physicochemical Properties of Three Types of Rice Bran Meal Dietary Fiber and Their Hypolipidemic Effects on Rats

“…The AI of hyperlipidemic rats of the PC group, H-RBDF group, N-RBDF group and E-RBDF group decreased to different degrees, in addition the AI of rats in the H-RBDF and E-RBDF groups was significantly lower than that in the MC group (p < 0.05), and the effect of E-RBDF intervention treatment was the best. Similarly, Dabour et al [53] found that yogurt supplemented with wheat bran or dietary fiber significantly (p < 0.05) reduced AI in hypercholesterolemic rats.…”

Physicochemical Properties and Hypolipidemic Activity of Dietary Fiber from Rice Bran Meal Obtained by Three Oil-Production Methods

“…In addition, the AI of rats in the H-RBDF and E-RBDF groups was significantly smaller than that in the MC group (p < 0.05), and the effect of E-RBDF intervention treatment was the best. Similarly, Dabour et al [54] found that yogurt supplemented with wheat bran or dietary fiber significantly (p < 0.05) reduced AI in hypercholesterolemic rats. hydraulic-pressed rice bran meal dietary fiber, n-hexane-leached rice bran meal dietary fiber, enzyme-method rice bran meal dietary fiber, respectively.…”

Exploring the cholesterol‐lowering effects of cereal bran cell wall‐enriched diets

“…Dabour et al. ( 2022 ) also probed the effects of barley bran and oat bran dietary fibers on liver cholesterol range. This diet (including dietary cholesterol) decreased serum LDL, liver cholesterol, and liver lipid and raised HDL and HDL/LDL cholesterol ratios (Noreen, Tufail, Badar Ul Ain, et al., 2023 ).…”

“…Merali et al found that hydrothermal pretreatment opens wheat bran cell walls, breaks down, solubilizes, and hydrolyzes hemicellulosic arabinoxylans and glucose, and reduces crosslinking phenolic acids (Merali et al, 2015;Tufail et al, 2018;. Dabour et al (2022) also probed the effects of barley bran and oat bran dietary fibers on liver cholesterol range. This diet (including dietary cholesterol) decreased serum LDL, liver cholesterol, and liver lipid and raised HDL and HDL/ LDL cholesterol ratios .…”