The ability of peripheral quantitative ultrasound to identify patients with low bone mineral density in the hip or spine

The role of quantitative ultrasound in predicting osteoporosis defined by dual-energy X-ray absorptiometry in pre- and postmenopausal women

“…This may be because QUS reflects micro-architectural or other mechanical properties of bone. Although there is enough evidence to support the use of QUS as an independent predictor of fracture risk and statistically significant correlations between DXA and QUS parameters 44 , our study shows that QUS should not be seen as a substitute for BMD measurement. Whether the same is true in premenopausal women is unclear, and further research is required comparing bone biopsies with QUS and DXA parameters in order to answer this question.…”

Ultrasonic attenuation estimation of the pregnant cervix: a preliminary report

“…Local ultrasonic attenuation has been successfully used to characterize the structure and health of biological tissues. Applications have included diagnosing diffuse liver disease42–45, monitoring tissue changes after high‐intensity ultrasound therapy46, assessing changes in the liver following prednisone treatment47, differentiating between benign and malignant tissue in the prostate48 and assessing the mineral content of bone49–52. Attenuation of tissue has been observed to decrease significantly as water concentration increases and density decreases53, 54.…”

Application of the dual-frequency ultrasonometer for osteoporosis detection

“…In general, there is poor agreement between data provided by existing commercial QUS of the axial type in long bones and bone status assessed by DXA, as revealed by Kappa and ROC analyses [12, 33]. Consequently, the conventional QUS, especially axial QUS, is hardly ever used for monitoring the bone condition in metabolic diseases or for predicting fracture risk.…”