The 8-Iso-PGF2a/PGF2a Ratio Quantitatively Measures Chemical Lipid Peroxidation in Animal Models

Erve, Thomas J van't; Lih, Fred B.; Jelsema, Casey; Kadiiska, Maria B.; Deterding, Leesa J.; Eling, Thomas E.; Mason, Ronald P.

doi:10.1016/j.freeradbiomed.2015.10.056

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Certain Oxidative Biomarkers Have Linked Oxidative Stress An1

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2018

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“…A substantial body of evidence indicates that measurement of prostaglandine (PG) like compounds provides a direct and reliable approach to assess oxidative damage in vivo compared with other methods such as thiobarbituric acid reacting substances TBARS that have been also widely studied [14]. According to Barocas et al (2011) [15].…”

Section: Certain Oxidative Biomarkers Have Linked Oxidative Stress Anmentioning

confidence: 99%

Effect of Natural Food Antioxidants Against LDL and DNA Oxidative Changes

Kiokias

Proestos²,

Oreopoulou³

2018

Preprint

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Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways, cause extensive oxidative damage, which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free-radicals initiated processes of LDL oxidative modification and DNA oxidative damage, which are widely associated to the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the potential of natural antioxidant compounds (such as carotenoids, vitamins C and E) to monitor LDL and DNA oxidative changes.

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Section: Certain Oxidative Biomarkers Have Linked Oxidative Stress Anmentioning

confidence: 99%