The 5-Year Course of Obsessive-Compulsive Symptoms and Obsessive-Compulsive Disorder in First-Episode Schizophrenia and Related Disorders

Abstract

The 5-year course of OCS/OCD in patients with first-episode schizophrenia or related disorders is variable. OCS/OCD comorbidity was not associated with a more severe course of psychotic symptoms and relapse. Comorbid OCD was associated with more severe depressive symptoms, social dysfunction and worse premorbid functioning. Specific treatment options for schizophrenia patients with comorbid OCD are needed.

Obsessive–compulsive symptom severity in schizophrenia: a Janus Bifrons effect on functioning

“…In fact, the few studies about this topic maintained a categorical approach (sub-threshold OCS vs full-blown OCD) [10,11].…”

“…The reason underlying the discrepancy across studies has been related to a phase-dependent effect of OC dimension on level of functioning, i.e., protective in early stages and deleterious in the later phases of the illness [9]. More recently, a 5-year follow-up study [10] has suggested that the severity of OC features might differentially impact social functioning in schizophrenia, with sub-threshold symptoms showing an improving effect and full-blown OCD a worsening one: Among patients with schizophrenia, those with OCS showed a better social functioning than both patients without OCS and with OCD. By contrast, a previous crosssectional study [11] found no significant differences in social functioning between schizophrenia patients with OCS and OCD.…”

Delusion or Obsession: Clinical Dilemma

“…In the current case, the patient was observed for improvement on the changed antipsychotic medication. A study [3] describes comorbid OCD with schizophrenia. In this, they mention that OCD was associated with more severe depressive symptoms, social dysfunction and worse premorbid functioning.…”

Validity and reliability of DSM-5 Level 1 Cross-Cutting Symptom Scale Turkish Version (Child Form for 11-17 Years and Parent Form for 6-17 Years)

“…Bir çalışmada şizofreni, şizofreniform bozukluk ve şizoaffektif bozukluk tanısı konan olgular beş yıl boyunca izlenmiş ve farklı değerlendirmelerde obsesif kompulsif belirtilerinin görülme oranının %22.7-30.6 arasında, obsesif kompulsif bozukluk tanısının %7.3-11.8 arasında değiştiği saptanmış ve bu birlikteliği açıkladığı düşünül-müştür. 17 …”