The “3 Genomic Numbers” Discovery: How Our Genome Single-Stranded DNA Sequence Is “Self-Designed” as a Numerical Whole

Abstract

This article proves the existence of a hyper-precise global numerical meta-architecture unifying, structuring, binding and controlling the billion triplet codons constituting the sequence of single-stranded DNA of the entire human genome. Beyond the evolution and erratic mutations like transposons within the genome, it's as if the memory of a fossil genome with multiple symmetries persists. This recalls the "intermingling" of information characterizing the fractal universe of chaos theory. The result leads to a balanced and perfect tuning between the masses of the two strands of the huge DNA molecule that constitute our genome. We show here how codon populations forming the single-stranded DNA sequences can constitute a critical approach to the understanding of junk DNA function. Then, we suggest revisiting certain methods published in our 2009 book "Codex Biogenesis". In fact, we demonstrate here how powerful a analytical filter the universal genetic code table is to characterize single-stranded DNA sequences constituting chromosomes and genomes. We can then show that any genomic DNA sequence is featured by three numbers, which characterize it and its 64 codon populations with correlations greater than 99%. The number "1" is common to all sequences, expressing the second law of Chargaff. The other 2 numbers are related to each specific DNA sequence case characterizing life species. For example, the entire human genome is characterized by three remarkable numbers 1, 2, and Phi = 1.618 the golden ratio. Associated with each of these three numbers, we can match three axes of symmetry, then "imagine" a kind of hyperspace formed by these codon populations. Then we revisit the value (3-Phi)/2 which is probably universal and common to both the scale of quarks and atomic levels, balancing and tuning the whole human genome codon population. Finally, we demonstrate a new kind of duality between "form and substance" overlapping the whole human genome: we will show that-simultaneously with the duality between genes and junk DNA-there is a second layer of embedded hidden structure overlapping all the DNA of the whole human genome, dividing it into a second type of duality information/redundancy involving golden ratio proportions.

Deciphering Hidden DNA Meta-Codes -The Great Unification & Master Code of Biology

“…Since 1997, this discovery has been improved across multiple segments of biology, genetics and genomics. These results have been only partially published [13][14][15][16][17] and in the drafts [18][19][20]. Our central discovery (methods and algorithms) will be now fully revealed in this article then in a series of others in preparation [21][22][23][24].…”

CRISPR Technology Challenge Facing the Numerical Integrity of Whole Human Genome DNA

“…We have already demonstrated a numerical structure at the scale of each human chromosome as well as on the whole genome [7][8][9][10][11][12][13][14][15]. In [10] we have already highlighted this numerical value of 0.6909830056, the HGO in this article: it controls the population of triplets codons analysing single stranded DNA sequence from the whole human genome.…”

Why the genomic LOCATION of individual SNPs is FUNCTIONAL?

“…On the other hand, we have discovered and published a law and a method of analysis: the "master code of DNA" [7,8], which UNIFIES all the information of the 3 types of CODES of Biology: DNA, RNA and amino acid sequences. Other numerical codes of DNA and genomes were discovered during these 25 years [ 8,9,10,11]. Some of these codes, as will be the case here, are fractal [12,13,14,15,16,17,18].…”