The 2020 update of the CEAP classification system and reporting standards

Lurie, Fedor; Passman, Marc A.; Meisner, Mark J.; Dalsing, Michael C.; Masuda, Elna M.; Welch, Harold J.; Bush, Ruth L.; Blebea, John; Carpentier, Patrick; Maeseneer, M. De; Gasparis, Anthony; Labropoulos, Nicos; Marston, William A.; Rafetto, Joseph; Santiago, Fabricio; Shortell, Cynthia K.; Uhl, J. F.; Urbanek, Tomasz; Rij, André van; Eklöf, B; Gloviczki, Péter; Kistner, Robert L.; Lawrence, Peter F.; Moneta, Gregory L.; Padberg, Frank T.; Perrin, Michel; Wakefield, Thomas W.

doi:10.1016/j.jvsv.2019.12.075

Cited by 420 publications

(258 citation statements)

References 42 publications

Supporting

Mentioning

225

Contrasting

Unclassified

Order By: Relevance

“…• 18-70 years old • C2,3EpAsPr with visible varicose veins. 16 • VCSS from 6 to 8 GSV caliber at 15 cm from the SFJ, and related hemodynamics were reported in Table 1.…”

Section: Study Design and Populationmentioning

confidence: 99%

Segmental saphenous ablation for chronic venous disease treatment

et al. 2020

View full text Add to dashboard Cite

Background Endovenous thermal ablation for chronic venous disease treatment is recommended over traditional surgery. The present investigation compares endovenous laser ablation (EVLA) with radiofrequency (RF) for segmental endovenous sapheno–femoral junction ablation. Methods This is a retrospective study in which 79 patients underwent a 6 cm great saphenous vein ablation by RF or by EVLA. Primary outcome was occlusion rate. Secondary outcomes included Venous Clinical Severity Score (VCSS), Aberdeen Varicose Vein Questionnaire (AVVQ) score, peri-procedural pain, aesthetic satisfaction. Results At 12 ± 1 months recanalization of shrunk tract was recorded in 5/85 (5.8%) cases (2 RF, 3 EVLA) [OR: 1.6; 95%CI: 0.2–10.4; P = 0.6689]. Two cases (1/44 RF group and 1/38 EVLA group) also showed reflux recurrence [OR: 1.0; 95%CI: 0.06–17.8; P = 1.0000]. No significant differences between groups were found in AVVQ, VCSS, peri-procedural pain, or aesthetic satisfaction. Conclusion Saphenous sparing is feasible and effective by means of both EVLA and RF, representing a possible alternative to surgery.

show abstract

“…• 18-70 years old • C2,3EpAsPr with visible varicose veins. 16 • VCSS from 6 to 8 GSV caliber at 15 cm from the SFJ, and related hemodynamics were reported in Table 1.…”

Section: Study Design and Populationmentioning

confidence: 99%

Segmental saphenous ablation for chronic venous disease treatment

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Preoperative GSV diameter was measured and patients were classified according to CEAP classification (clinical, etiological, anatomical, and pathophysiological). 7…”

Section: Methodsmentioning

confidence: 99%

Comparative efficacy and life quality effects of surgical stripping, radiofrequency ablation, and cyanoacrylate embolization in patients undergoing treatment for great saphenous vein insufficiency

Güneş

Turkkolu

et al. 2020

Phlebology

View full text Add to dashboard Cite

Objectives To compare traditional surgery with two minimally invasive endo-venous procedures in terms of their long-term effect on the quality of life in great saphenous vein insufficiency (GSV). Method This prospective observational study included 217 patients that underwent surgical stripping (n = 62), radiofrequency ablation (n = 70), or cyanoacrylate embolization (n = 85) for the treatment of GSV insufficiency. Venous Clinical Severity Score (VCSS) assessments were made, 36-item Short-Form Health Survey (SF-36) questionnaire and Chronic Venous Insufficiency quality of life Questionnaire (CIVIQ-14) were administered, before and 1 year after the treatments. Results Surgical stripping group had significantly higher closure rates than the other groups (p < 0.05). At 12 months, decrease in VCSS scores was less pronounced in the cyanoacrylate embolization group when compared to the other two groups (p < 0.05). Improvement in CIVIQ-14 scores was better in the radiofrequency ablation group when compared to the cyanoacrylate embolization group (p < 0.05). Surgical stripping or radiofrequency ablation groups performed better on several domains of SF-36, when compared to the cyanoacrylate embolization group. Conclusions Surgical stripping and radiofrequency ablation seem to provide a better quality of life results at one year in patients undergoing treatment for GSV insufficiency.

show abstract

“…CVD is defined as a syndrome of chronic morphological and functional abnormalities of the venous system, manifested either by symptoms (including tingling, aching, burning, pain, muscle cramps, swelling, sensations of throbbing or heaviness, itching, restless legs, leg tiredness and fatigue) or clinical signs prompting the need for investigation and medical care [3]. The disease encompasses a wide spectrum of clinical presentations such as telangiectasia, varicose veins, leg edema, skin changes and ulcers, as included in the Clinical, Etiology, Anatomic, Pathophysiology (CEAP) classification [4][5][6]. Chronic Venous Insufficiency (CVI) is a term reserved for advanced CVD, which is applied to functional abnormalities of the venous system producing edema, skin changes, or venous ulcers (C3-C6 in CEAP classification) [3].…”

Section: Introductionmentioning

confidence: 99%

Dysregulations of MicroRNA and Gene Expression in Chronic Venous Disease

Zalewski

Ruszel

Stępniewski

et al. 2020

JCM

View full text Add to dashboard Cite

Chronic venous disease (CVD) is a vascular disease of lower limbs with high prevalence worldwide. Pathologic features include varicose veins, venous valves dysfunction and skin ulceration resulting from dysfunction of cell proliferation, apoptosis and angiogenesis. These processes are partly regulated by microRNA (miRNA)-dependent modulation of gene expression, pointing to miRNA as a potentially important target in diagnosis and therapy of CVD progression. The aim of the study was to analyze alterations of miRNA and gene expression in CVD, as well as to identify miRNA-mediated changes in gene expression and their potential link to CVD development. Using next generation sequencing, miRNA and gene expression profiles in peripheral blood mononuclear cells of subjects with CVD in relation to healthy controls were studied. Thirty-one miRNAs and 62 genes were recognized as potential biomarkers of CVD using DESeq2, Uninformative Variable Elimination by Partial Least Squares (UVE-PLS) and ROC (Receiver Operating Characteristics) methods. Regulatory interactions between potential biomarker miRNAs and genes were projected. Functional analysis of microRNA-regulated genes revealed terms closely related to cardiovascular diseases and risk factors. The study shed new light on miRNA-dependent regulatory mechanisms involved in the pathology of CVD. MicroRNAs and genes proposed as CVD biomarkers may be used to develop new diagnostic and therapeutic methods.

show abstract

The 2020 update of the CEAP classification system and reporting standards

Cited by 420 publications

References 42 publications

Segmental saphenous ablation for chronic venous disease treatment

Segmental saphenous ablation for chronic venous disease treatment

Comparative efficacy and life quality effects of surgical stripping, radiofrequency ablation, and cyanoacrylate embolization in patients undergoing treatment for great saphenous vein insufficiency

Dysregulations of MicroRNA and Gene Expression in Chronic Venous Disease

Contact Info

Product

Resources

About