The 2018 Global Point Prevalence Survey of antimicrobial consumption and resistance in 47 Canadian hospitals: a cross-sectional survey

Abstract

A ntimicrobial resistance is a substantial threat to public health 1 and increases mortality, morbidity and health care costs. 2 Antimicrobial overuse and misuse accelerates the development of antimicrobial resistance. 1,3 A global response is warranted to ensure rational antimicrobial use (AMU), given that antimicrobial resistance is commutable between countries. In 2017, Canada

A Retrospective, Longitudinal External Study of the robustness and reproducibility of National Antibacterial Prescribing Survey Data

“…Globally and in Australian hospitals, the main indications for antimicrobial prescriptions were pneumonia, SSTI and surgical prophylaxis [ 10 , 29 ]. In this study, surgical prophylaxis accounted for 12.2% of antibacterial usage, which was higher than that reported in Canadian hospitals (8.9%)[ 11 ] and in Switzerland (9.1%)[ 27 ], but more closely aligned with the average five year NAPS rates (13.4%) in Australia [ 26 , 28 , 30 – 32 ]. This hospital reported a lower rate of antibacterial prescribing for CAP (7.8%) than national NAPS (11.4%) and Canadian data (14.4%)[ 11 ].…”

“…In this study, surgical prophylaxis accounted for 12.2% of antibacterial usage, which was higher than that reported in Canadian hospitals (8.9%)[ 11 ] and in Switzerland (9.1%)[ 27 ], but more closely aligned with the average five year NAPS rates (13.4%) in Australia [ 26 , 28 , 30 – 32 ]. This hospital reported a lower rate of antibacterial prescribing for CAP (7.8%) than national NAPS (11.4%) and Canadian data (14.4%)[ 11 ]. Similarly, antibacterial use for the treatment of HAP in this hospital (4.0%) was lower than 9.1% reported in Canada [ 11 ].…”

“…Antibacterial agents prescribed in this hospital showed similar trends as national [ 26 ] and international [ 10 , 11 , 27 ] PPS. The most frequently prescribed antibacterial agents were penicillin-beta lactamase inhibitor combinations and first and third generation cephalosporins.…”

“…This hospital reported a lower rate of antibacterial prescribing for CAP (7.8%) than national NAPS (11.4%) and Canadian data (14.4%)[ 11 ]. Similarly, antibacterial use for the treatment of HAP in this hospital (4.0%) was lower than 9.1% reported in Canada [ 11 ]. Pneumonia treatment was the most common indication (19.2%) in a global PPS of 53 countries [ 10 ].…”

“…Different countries utilise PPS to evaluate and report on the appropriateness of their antimicrobial consumption [ 10 , 11 ]. A PPS of Australian adult hospital patients reported an inappropriate antibacterial prescribing rate of 47% [ 12 ].…”