The 2009 A (H1N1) influenza virus pandemic: A review

Girard, Marc; Tam, John S.; Assossou, Olga; Kiény, Marie Paule

doi:10.1016/j.vaccine.2010.05.031

Cited by 411 publications

(367 citation statements)

References 102 publications

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“…However, further evolution of the strain might occur without such closures. And because individuals with underlying severe illnesses become critical or even die due to H1N1 infection [5], and the incidence rate of patients with critical illnesses might have increased if the school closure measure had not been applied, we concluded that the school closure measure was necessary to reduce transmission regardless of low virus toxicity. While vaccination is shown to be the most important infection control measure [24], epidemic control measures without vaccine must be taken when insufficient vaccine is available.…”

Section: Discussionmentioning

confidence: 98%

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Effect of short-term school closures on the H1N1 pandemic in Japan: a comparative case study

et al. 2012

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Purpose. The 2009 worldwide influenza A/H1N1 pandemic particularly affected younger people, including schoolchildren. We assessed the effects of class/school closure during the pandemic on the spread of H1N1 infection in Japan. Methods. We prospectively monitored 2141 schoolchildren in 57 classes at 2 elementary schools and 2 junior high schools in Japan, and we evaluated the effects of class/school closures on the spread of H1N1 using descriptive epidemiological methods.Results. The cumulative rate of H1N1 infection among these children was 40.9% (876 children). There was a total of 53 closures of 40 classes, including school closures, during the pandemic. Time-course changes in the epidemic curve showed that school closure reduced the following epidemic peak more than class closure. A Poisson regression model showed that a longer duration of closure was significantly related to decreased H1N1 occurrence after the resumption of classes. Conclusions. School closure more effectively inhibits subsequent epidemic outbreaks than class closure. Longer school closures are effective in reducing the spread of infection, and school closure should be implemented as early as possible.

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Section: Discussionmentioning

confidence: 98%

“…At the end of the pandemic, it became clear that H1N1 had spread more among younger people than older people [3][4][5][6][7][8], and there were many infections among schoolchildren [9][10][11]. Measures instituted to prevent the transmission of H1N1 included school closures [12][13][14][15].…”

mentioning

confidence: 99%

Effect of short-term school closures on the H1N1 pandemic in Japan: a comparative case study

et al. 2012

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“…Several viral diseases were observed to be a threat to public health due to this factor. The Severe Acute Respiratory Syndrome (SARS) outbreak in 2003, the recent outbreak of Middle East Respiratory Syndrome-Corona virus (MERS-CoV) in Korea [16] and the global spread of the swineorigin influenza A-H1N1 in 2009 emerging from Mexico and USA [17] are typical examples of this. The emergence and rapid spread of chikungunya virus in the America's in 2013/2014 [18] and the rapid spread of Ebola virus in West Africa and its introduction into North America and Europe in 2014 by returning travelers and health-care workers [19] are recent replicates of the travelling factor.…”

Section: Mini Review Abstractmentioning

confidence: 99%

Viral Zoonosis Control and Erradication: Best Addressed Through One Health Approach

Haroun¹

2015

JHVRV

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“…The influenza pandemic of 2009 was caused by a novel strain of influenza A(H1N1)pdm09, which was first identified in Mexico and then spread globally. It had a massive impact on the health and economy of all affected regions (3,4). Genetic analysis confirmed that it was a triple reassorted virus, with polymerase basic (PB)1 from viruses of human origin, HA, nucleoprotein (NP) and non-structural (NS) genes from classical swine virus, PB2 and polymerase A (PA) from North American avian viruses and NA and matrix (M) from Eurasian swine avian-like viruses (5,6).…”

Section: Introductionmentioning

confidence: 99%

Molecular epidemiology and evolution of A(H1N1) pdm09 and H3N2 viruses in Jordan, 2011-2013

El-Shesheny

Halasa

Williams

et al. 2016

East Mediterr Health J

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Understanding the genetic evolution of A(H1N1)pdm09 and H3N2 viruses can help better select strains to be included in the annual influenza vaccine. There is little information on their evolution in Jordan so this study investigated the genetic and antigenic variability of A(H1N1)pdm09 and H3N2 viruses in Jordan by performing phylogenetic and genetic analyses of the HA and NA genes of A(H1N1)pdm09 and H3N2 viruses between 2011 and 2013. The full HA and NA genes of 16 H1N1-positive samples obtained in our study and 21 published HA sequences and 20 published NA sequences from Jordanian viruses that were available on online gene databases were analysed. For H3N2, we generated 20 HA and 19 NA sequences and included 19 published HA and NA sequences each in the analysis. Jordanian H1N1 viruses had mutations that are characteristic of antigenic group 6 while H3N2 virus mutations belonged to group 3. No markers of resistance to oseltamivir were detected. The individual mutations are described in detail.

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The 2009 A (H1N1) influenza virus pandemic: A review

Cited by 411 publications

References 102 publications

Effect of short-term school closures on the H1N1 pandemic in Japan: a comparative case study

Effect of short-term school closures on the H1N1 pandemic in Japan: a comparative case study

Viral Zoonosis Control and Erradication: Best Addressed Through One Health Approach

Molecular epidemiology and evolution of A(H1N1) pdm09 and H3N2 viruses in Jordan, 2011-2013

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