The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: Design, Epidemiological Methods and Descriptive Results

Vrijheid, Martine; Cardis, Elisabeth; Blettner, Maria; Gilbert, Ethel S.; Hakama, Matti; Hill, Catherine; Howe, Geoffrey R.; Kaldor, John; Muirhead, Colin R.; Schubauer‐Berigan, Mary K.; Yoshimura, Takesumi; Yo, Ahn; Ashmore, Patrick; Auvinen, Anssi; Jm, Bae; Engels, Hilde; Gulis, Gabriel; Rr, Habib; Hosoda, Yutaka; Kurtinaitis, Juozas; Malker, Hans; Moser, Mirjana; Rodríguez‐Artalejo, Fernando; Rogel, A.; Tardy, Hélène; Telle-Lamberton, M.; Turai, I; Usel, M.; Veress, K.

doi:10.1667/rr0554.1

Cited by 122 publications

(60 citation statements)

References 32 publications

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“…A healthy worker effect is often observed in occupational cohorts, especially in nuclear workers Vrijheid et al, 2007b;Hammer et al, 2008;Muirhead et al, 2009;SchubauerBerigan et al, 2015). This well-known effect is generally due to various employment-related components, mainly the healthy hire effect that occurs as healthy people are more likely to enter the workforce than less healthy people and the healthy survivor effect that refers to the process whereby healthy workers remain employed longer than less healthy workers (Howe et al, 1988;Baillargeon, 2001).…”

Section: Cancer Mortalitymentioning

confidence: 99%

“…Populations of nuclear workers are particularly relevant to study potential health effects of low dose and low dose-rate exposures to IR, and cohorts of nuclear workers were implemented worldwide (Vrijheid et al, 2007b). The interest of these studies relies in particular on the availability of individual annual occupational doses monitored in the frame of the radiation protection surveillance.…”

Section: Introductionmentioning

confidence: 99%

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Mortality in the French cohort of nuclear workers

et al. 2017

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-Populations of nuclear workers are particularly relevant to study health effects of protracted exposures to low doses at low dose-rates of ionizing radiation. In France, a cohort of nuclear workers employed by the Commissariat à l'énergie atomique et aux énergies alternatives (CEA), AREVA Nuclear Cycle (AREVA NC), or Électricité de France (EDF), and badge-monitored for external radiation exposure, has been followed-up for several decades. Annual exposure to penetrating photons was reconstructed for each worker. Standardized mortality ratios were calculated using national mortality rates as the reference. Estimates of radiation dose-mortality associations were obtained using linear excess relative risk models. Mortality of 59 004 workers was followed-up between 1968 and 2004, for an average of 25 years. The mean cumulative photon H p (10) dose was 18.4 mSv in the whole cohort (median value: 2.1 mSv) and 25.7 mSv among exposed workers. At the end of the follow-up, workers were 56 years old on average and 6310 workers had died. A strong healthy worker effect was observed. Estimated dose-risk relationships were consistent with those from other worker studies for all solid cancers and leukaemia excluding chronic lymphocytic leukaemia, but remained associated to a large uncertainty. This cohort is the most informative study ever conducted in France among nuclear workers.

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Section: Cancer Mortalitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Mortality in the French cohort of nuclear workers

et al. 2017

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“…In such situation one could immediately say that conventional least-square fitting must lead to the parameters of the fit that may not be reliable. It could be suspected that the conclusions reached in papers [3] were due to a few "outliers" in the data. In fact, in the data considered one cannot directly say which points should be treated as outliers just because of the scatter of the data.…”

Section: "Outliers" and Curve Fittingmentioning

confidence: 99%

“…The scatter of points presented in original papers [3], that were intended to show that the risk of cancer death increases with the dose absorbed by workers, by far exceeded declared experimental uncertainties. These points exhibited also uneven distribution of points along abscissa axis.…”

Section: "Outliers" and Curve Fittingmentioning

confidence: 99%

Application of Bayesian Reasoning and the Maximum Entropy Method to Some Reconstruction Problems

et al. 2010

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The so-called Bayesian reasoning is applied whenever uncertainty has to be considered as serious factor in interpretation of results. The paper presents analysis of the impact of inaccurate data on the straight line and quadratic relation fittings. This type of analysis is particularly important when one tries to decide on the type of dependence. The paper also shows examples of the Maximum Entropy Methods applied to the reconstruction of the hyperfine parameters distribution from the measured Mössbauer spectra of GaFeO 3 and the electron-positron momentum distribution from the positron annihilation data of Gd.

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“…Bu çalışma dozimetre ölçümlerinin net olması, farklı etnik grupları içermesi ve ortalama dozun BT 'de alınan doza çok yakın olması nedeniyle değerli bir veri sunmaktadır. Öte yandan, mortalitenin sadece Kanada'daki işçilerde görülmesi ve farklılığın akciğer kanserindeki artıştan kaynaklanıyor olması, sigara gibi çevresel faktörlerin etkisi hesaba katılmadığı için verilerin değerini azaltmaktadır (23).…”

Section: Radyasyonunclassified

Cardiac computed tomography and radiation

Sezenöz¹,

Şahinarslan²

2013

Anadolu Kardiyol Derg

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Son yıllardaki teknik gelişmeler nedeniyle kardiyovasküler hastalıkların tanısında bilgisayarlı tomografinin yeri gün geçtikçe artmaktadır. Ancak bu işlem sırasında kullanılan radyasyon dozu, buna bağlı oluşabilecek potansiyel sonuçlar konusunda tartışma yaratmaktadır. Elimizde henüz bilgisayarlı tomografide kullanılan radyasyon dozunun yol açabileceği istenmeyen etkiler konusunda net veriler bulunmamaktadır. Bu derlemede bilgisayarlı tomografi ve radyasyon riski ile ilgili literatürdeki veriler gözden geçirilmiştir. Bilgisayarlı tomografide kullanılan radyasyon dozunu azaltmak için alınabilecek önlemlerin başında testin doğru endikasyonla, uygun hastada yapılması gelmektedir. Bunun yanında son yıllarda geliştirilen radyasyon azaltıcı teknolojiler ve kişiye özgü çekim teknikleri sayesinde kullanılan radyasyon dozu belirgin ölçüde azaltılabilmektedir. Klinisyenlerin radyasyon riskinin azaltılması açısından kullanılması gereken teknikler konusunda bilgi sahibi olmaları ve çalıştıkları merkezdeki teknik olanakların farkında olmaları önem taşımaktadır. ABSTRACTWith the recent technological developments, computed tomography is becoming more important in the diagnosis of cardiovascular diseases. However, potential complications of the radiation dose used during the test have led debates. In the current situation, the data about undesirable effects of radiation dose used in cardiac computed tomography is not clear. In this paper, we reviewed the data about computed tomography and the risk of radiation. In order to reduce the risk of radiation due to computed tomography, the test should be performed with proper indication and in suitable patients. Besides, recently developed radiation dose reduction technologies and patient specific protocols have significantly reduced the radiation exposure. The clinicians should be well informed about the radiation reduction techniques and aware of the technical capabilities in their hospital. (Anadolu Kardiyol Derg 2013; 13: 374-8)

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The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: Design, Epidemiological Methods and Descriptive Results

Cited by 122 publications

References 32 publications

Mortality in the French cohort of nuclear workers

Mortality in the French cohort of nuclear workers

Application of Bayesian Reasoning and the Maximum Entropy Method to Some Reconstruction Problems

Cardiac computed tomography and radiation

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