That antibiotic prophylaxis should be used in children with repaired oesophageal atresia and or trachea-oesophageal fistula – The case in favour

Merkus, Peter

doi:10.1016/j.prrv.2015.11.003

Cited by 5 publications

(8 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Borrowing primarily from the experience in patients with cystic fibrosis, [148][149][150] there was a borderline strong agreement on the use of prophylactic azithromycin due to its antimicrobial and antiinflammatory properties for patients with chronic symptoms, especially those with documented bronchiectasis. 151,152 However, there was only moderate agreement on using antibiotics in asymptomatic children who have positive BAL cultures especially with organisms are considered to be "normal" oral flora.…”

Section: Antibiotic Therapymentioning

confidence: 99%

Care recommendations for the respiratory complications of esophageal atresia‐tracheoesophageal fistula

Koumbourlis

Belessis

Cataletto

et al. 2020

Pediatric Pulmonology

View full text Add to dashboard Cite

Tracheoesophageal fistula (TEF) with esophageal atresia (EA) is a common congenital anomaly that is associated with significant respiratory morbidity throughout life. The objective of this document is to provide a framework for the diagnosis and management of the respiratory complications that are associated with the condition. As there are no randomized controlled studies on the subject, a group of experts used a modification of the Rand Appropriateness Method to describe the various aspects of the condition in terms of their relative importance, and to rate the available diagnostic methods and therapeutic interventions on the basis of their appropriateness and necessity. Specific recommendations were formulated and reported as Level A, B, and C based on whether they were based on “strong”, “moderate” or “weak” agreement. The tracheomalacia that exists in the site of the fistula was considered the main abnormality that predisposes to all other respiratory complications due to airway collapse and impaired clearance of secretions. Aspiration due to impaired airway protection reflexes is the main underlying contributing mechanism. Flexible bronchoscopy is the main diagnostic modality, aided by imaging modalities, especially CT scans of the chest. Noninvasive positive airway pressure support, surgical techniques such as tracheopexy and rarely tracheostomy are required for the management of severe tracheomalacia. Regular long‐term follow‐up by a multidisciplinary team was considered imperative. Specific templates outlining the elements of the clinical respiratory evaluation according to the patients’ age were also developed.

show abstract

Section: Antibiotic Therapymentioning

confidence: 99%

Care recommendations for the respiratory complications of esophageal atresia‐tracheoesophageal fistula

Koumbourlis

Belessis

Cataletto

et al. 2020

Pediatric Pulmonology

View full text Add to dashboard Cite

show abstract

“…Borrowing primarily from the experience in patients with Cystic Fibrosis [146][147][148] , there was strong agreement on the use of prophylactic azithromycin due to its antimicrobial and anti-inflammatory properties for patients with chronic symptoms, especially those with documented bronchiectasis 149,150 . However, there was only moderate agreement on using antibiotics in asymptomatic children who have positive BAL cultures especially with organisms are considered to be "normal" oral flora.…”

Section: Antibiotic Therapymentioning

confidence: 99%

Care Recommendations for the Respiratory Complications of Esophageal Atresia-Tracheoesophageal Fistula: The International Network of Esophageal Atresia, Respiratory Complications Working Group

Koumbourlis

Belessis

Cataletto

et al. 2020

Preprint

View full text Add to dashboard Cite

Tracheoesophageal fistula (TEF) with esophageal atresia (EA) is a common congenital anomaly that is associated with significant respiratory morbidity throughout life. The objective of this document is to provide a framework for the diagnosis and management of the respiratory complications that are associated with the condition. As there are no randomized controlled studies on the subject, a group of experts used a modification of the Rand Appropriateness Method to describe the various aspects of the condition in terms of their relative importance, and to rate the available diagnostic methods and therapeutic interventions on the basis of their appropriateness and necessity. Specific recommendations were formulated and reported as Level A, B, C based on whether they were based on "strong", "moderate" or "weak" agreement. The tracheomalacia that exists in the site of the fistula was considered the main abnormality that predisposes to all other respiratory complications due to airway collapse and impaired clearance of secretions. Aspiration due to impaired airway protection reflexes is the main underlying contributing mechanism. Flexible bronchoscopy is the main diagnostic modality, aided by imaging modalities, especially CT scans of the chest. Non-invasive positive airway pressure support, surgical techniques such as tracheopexy and rarely tracheostomy are required for the management of severe tracheomalacia. Regular long-term follow-up by a multidisciplinary team was considered imperative. Specific templates outlining the elements of the clinical respiratory evaluation according to the patients' age were also developed.

show abstract

“…Die Diskussion in der AG kann dazu genutzt werden, die Argumente für oder gegen eine PAP noch einmal sorgfältig abzuwägen und weitere Aspekte des Präventionsbündels (wie z. B. die Antisepsis der Haut) gemeinsam zu diskutieren [9,10,44]. Interventionen, die auf eine Standardisierung der klinischen Praxis im Bereich der PAP abzielen, sind für diejenigen, die sie einführen möchten, keine "low hanging fruits".…”

Section: Etablierung Von Internen Leitlinien Für Die Papunclassified

“…Kontrollierte Studien zur PAP bei Neonaten sind rar, bei den meisten Untersuchungen handelt es sich um retrospektive Kohortenstudien [8]. Der Mangel an wissenschaftlicher Evidenz aus randomisierten Studien erklärt einen Teil der Heterogenität in der klinischen Praxis [9,10]. Einige angeborene Fehlbildungen bei Neugeborenen, die einen chirurgischen Eingriff erfordern, sind so selten, dass randomisierte kontrollierte Studien zur PAP nur in mul-tizentrischen Forschungsnetzwerken durchführbar sind (z.…”

Section: Introductionunclassified

“…Einige angeborene Fehlbildungen bei Neugeborenen, die einen chirurgischen Eingriff erfordern, sind so selten, dass randomisierte kontrollierte Studien zur PAP nur in mul-tizentrischen Forschungsnetzwerken durchführbar sind (z. B. Inzidenz der Ösophagusatresie mit/ohne tracheoösophageale Fistel: 3 auf 10.000 Neugeborene) [10]. Eine übergeordnete AWMF Leitlinie der pädiatrischen Fachgesellschaften zur PAP befindet sich in Planung.…”

Section: Introductionunclassified

See 1 more Smart Citation

Update Perioperative Antibiotikaprophylaxe in der Neonatologie

Simon,

Meier,

Baltaci

et al. 2023

Z Geburtshilfe Neonatol

View full text Add to dashboard Cite

ZusammenfassungIn dieser Übersicht werden Grundprinzipien der perioperativen Antibiotikaprophylaxe (PAP) bei Früh- und Reifgeborenen diskutiert und es wird auf einige Besonderheiten bei den Indikationen und der Dosierung der PAP eingegangen. Auch wenn intensivmedizinisch behandelte Neugeborene eine vulnerable Patientengruppe darstellen, soll die PAP in ihrem Wirkspektrum gezielt und in der Regel nicht länger als 24 Stunden verabreicht werden.

show abstract

That antibiotic prophylaxis should be used in children with repaired oesophageal atresia and or trachea-oesophageal fistula – The case in favour

Cited by 5 publications

References 17 publications

Care recommendations for the respiratory complications of esophageal atresia‐tracheoesophageal fistula

Care recommendations for the respiratory complications of esophageal atresia‐tracheoesophageal fistula

Care Recommendations for the Respiratory Complications of Esophageal Atresia-Tracheoesophageal Fistula: The International Network of Esophageal Atresia, Respiratory Complications Working Group

Update Perioperative Antibiotikaprophylaxe in der Neonatologie

Contact Info

Product

Resources

About