Thallium - poisoner’s poison: An overview and review of current knowledge on the toxicological effects and mechanisms

Fujihara, Junko; Nishimoto, Naoki

doi:10.1016/j.crtox.2024.100157

Cited by 1 publication

(1 citation statement)

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“…The toxicity of thallium (Tl) is related to two of its chemical properties. Firstly, the toxic mechanism of Tl + is associated with potassium (K + ) ions [52]. The ionic radius of Tl + is similar to that of K + [53].…”

Section: Molecular Toxicity and Adverse Reactions Caused By Thalliummentioning

confidence: 99%

The Impact of Thallium Exposure in Public Health and Molecular Toxicology: A Comprehensive Review

Chang,

Chiang

2024

IJMS

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This review offers a synthesis of the current understanding of the impact of low-dose thallium (Tl) on public health, specifically emphasizing its diverse effects on various populations and organs. The article integrates insights into the cytotoxic effects, genotoxic potential, and molecular mechanisms of thallium in mammalian cells. Thallium, a non-essential heavy metal present in up to 89 different minerals, has garnered attention due to its adverse effects on human health. As technology and metallurgical industries advance, various forms of thallium, including dust, vapor, and wastewater, can contaminate the environment, extending to the surrounding air, water sources, and soil. Moreover, the metal has been identified in beverages, tobacco, and vegetables, highlighting its pervasive presence in a wide array of food sources. Epidemiological findings underscore associations between thallium exposure and critical health aspects such as kidney function, pregnancy outcomes, smoking-related implications, and potential links to autism spectrum disorder. Thallium primarily exerts cellular toxicity on various tissues through mitochondria-mediated oxidative stress and endoplasmic reticulum stress. This synthesis aims to shed light on the intricate web of thallium exposure and its potential implications for public health, emphasizing the need for vigilant consideration of its risks.

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Section: Molecular Toxicity and Adverse Reactions Caused By Thalliummentioning

confidence: 99%

The Impact of Thallium Exposure in Public Health and Molecular Toxicology: A Comprehensive Review

Chang,

Chiang

2024

IJMS

View full text Add to dashboard Cite

show abstract

Thallium - poisoner’s poison: An overview and review of current knowledge on the toxicological effects and mechanisms

Cited by 1 publication

References 115 publications

The Impact of Thallium Exposure in Public Health and Molecular Toxicology: A Comprehensive Review

The Impact of Thallium Exposure in Public Health and Molecular Toxicology: A Comprehensive Review

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