TGF-β signaling molecules in Hydra: role of BMP and BMP inhibitors during pattern formation
Lakshmi-Surekha Krishnapati,
Surendra Ghaskadbi
Abstract:Understanding the evolution of body plans has been one of the major areas of investigation in developmental and evolutionary biology. Cnidaria, the sister group to bilaterians, provides an opportunity to elucidate the origin and evolution of body axes. Hydra, a freshwater cnidarian, is a useful model to study signaling pathways governing pattern formation, which are conserved up to vertebrates including humans. The transforming growth factor β (TGF-β) signaling pathway is one of the fundamental pathways that r… Show more
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