Texture analysis of dorsal striatum in functional neurological (conversion) disorder

Abstract

In this study, it was aimed to evaluate the dorsal striatum nuclei of patients diagnosed with Functional Neurological Disorder by tissue analysis method from magnetic resonance imaging images and to compare them with healthy controls.Study groups consisted of 20 female patients and 20 healthy women. The brains of patients and controls were scanned for high-resolution images with a 1.5 T scanner using the sagittal plane and 3D spiral fast spin echo sequence. Using the texture analysis method, mean, standard deviation, minimum, maximum, median, variance, entropy, size %L, size %U, size %M, kurtosis, skewness and homogeneity values of the dorsal striatum nuclei were calculated from the images. The data were compared with comparison tests according to Kolmogorov-Smirnov test results.There was no statistically signi cant difference between paired regions in terms of texture analysis ndings in the cross-sectional images of the participants. In patients, mean, standard deviation, minimum, maximum, median, variance and entropy values for the putamen nucleus, and mean, standard deviation, minimum, maximum, median, variance, entropy and kurtosis values for the caudate nucleus were found signi cantly higher than controls. Additional receiver operating characteristic curve and logistic regression analyzes were performed.The implications of the results of the study are that there are signi cant microstructural changes in the dorsal striatum nuclei of patients and their re ection on brain images. Texture analysis is a useful technique to show tissue changes in the dorsal striatum of patients using images. It is highly recommended to use tissue analysis to identify and evaluate potentially affected areas of the brain in new studies.

Is the Caudate, Putamen, and Globus Pallidus the Delusional Disorder's Trio? A Texture Analysis Study

“…Histogram and fractal analysis texture analysis values obtained from ROIs have been previously described in the literature [ 23 , 25 , 26 , 30 , 31 ].…”

“…Texture properties are essentially mathematical parameters calculated from the pixel distribution obtained with the tissue type and therefore characterize the basic structure of the objects shown in the image. By quantitatively assessing the spatial variation and distribution of grayscale levels in the region of interest (ROI), it provides a more objective and detailed assessment of tissue characteristics than visual analysis by human observers [ 23 , 24 , 25 , 26 ]. Entropy measures parametric homogeneity in the ROI.…”

Dorsal Striatum in Obsessive-Compulsive Disorder: A Texture Analysis Study

“…Histogram values obtained from ROIs have been previously described in the literature (Baykara & Baykara, 2022;Baykara et al, 2021;Castellano et al, 2004;Materka, 2004).…”

“…Texture properties are essentially mathematical parameters calculated from the pixel distribution obtained with the tissue type and therefore characterize the basic structure of the objects shown in the image. By quantitatively assessing the spatial variation and distribution of grayscale levels in the region of interest (ROI), it provides a more objective and detailed assessment of tissue characteristics than visual analysis by human observers (Baykara & Baykara, 2022;Baykara et al, 2021;Castellano et al, 2004;Ganeshan et al, 2010).…”