“…Then, metallic ions were released into the surrounding tissues, altering the local tissue environment and generating further degradation. 28,29 The global conclusion of first generation explanted endograft analysis was that continuous movements as a result of the grafted aorta and blood pressure imposed permanent stress on the stent frame and polyester fabrics, resulting in frame dislocation of middle body rings, and that an optimal choice of a woven textile was mandatory for the construction of an endograft, as the textile properties, such as saturation index, may contribute to the macroscopic lesions observed on explanted devices. 26,27 Based on these conclusions, ePTFE was introduced as endograft material, combined with a thin, non-permeable layer of fluorinated ethylene propylene, all of which was attached to a nitinol stent frame, in order to reduce stent/ fabric degradation.…”