It is important to construct critical reading skills into the writing scientific papers process for students. It aims to strengthen the process and results of scientific writing so that the results are more profound. Therefore, this research was aims to reveal the basic concepts of critical reading in writing scientific papers for students and the relation between critical reading and the 21 st Century skills in writing scientific papers for students. The method used in this study is a critical analysis method through the following stages: (1) formulating research questions and hypotheses, (2) sampling the selected data sources, (3) making categories used in the analysis, (4) collecting the data on a sample of documents that have been selected and coding, (5) making scales and items based on certain criteria to collect the data, ( 6) interpreting the data obtained, and ( 7) conclusions. The results of the analysis found about two main things. First, critical reading skills have a strong influence on article writing skills, especially in the process of finding ideas and ideas, paragraph development, description analysis, content analysis, research results development, and concluding. Secondly, critical reading skills cannot be separated from the 21 st century skills, namely critical thinking and problem solving skills, creativity and innovation, collaboration, and communication.