Tetrazoles with oxygen-, sulfur-, and selenium-containing substituents

Zinc (II) Chloride as Phase Transfer Catalyst and as Catalyst of Cycloaddition Azide Ion to Heterocumulenes and Terminal Alkynes in Organic Solvents

“…1‐Substituted 1 H ‐tetrazole‐5‐thioles are widely used in the synthesis of biologically active substances and functional materials, moreover, they are valuable reagents in organic synthesis . These compounds are used in the olefination of carbonyl derivatives (Julia‐Kocienski Olefination), and can also be used for the preparation of 1‐substituted 1 H ‐tetrazoles, 1‐substituted 5‐bromo‐1 H ‐tetrazoles and 1‐substituted 1 H ‐tetrazole‐5‐ones …”

“…The primary method for the preparation of this type of compounds is cycloaddition of azide to triple (C≡N, C≡C) or cumulative double (N=C=X; X=NR’, O, S) bonds. The synthesis of 5‐substituted 1 H ‐tetrazoles from nitriles, isothiocyanates, isocyanates, and carbodiimides is the most common among these transformations (Scheme ).…”

“…In most cases, the cycloaddition requires prolonged heating of unsaturated compound in the presence of an azide source ‐ HN 3 , NaN 3 , TMSN 3 , etc . A catalyst is often added to the reaction mixture, while Lewis acids are most commonly used.…”

Synthesis and Properties of Dichlorovinyl Derivatives of Tetrazoles

“…Vinyl derivatives of (thio)tetrazoles attract attention as starting materials for the synthesis of high molecular weight compounds, biologically active substances, and functional materials [1][2][3][4][5]. Vinyltetrazole-based polymers are components of promising energy-intensive materials, gas separation membranes, nonwoven filter materials for medicine, and other composite materials [1,2].…”