Tetraventricular central neurocytoma: A rare presentation with imaging.pathologic correlation

Abstract

Central neurocytoma (CN) is a benign intraventricular neuronal tumor with a favorable prognosis. It accounts approximately 0.25–0.5% of intracranial tumors. In this report, we describe a very rare case of tetraventricular CN with imaging-pathologic correlation, and discuss their atypical features in a location together with treatment options. A 27-year-old man was admitted to the hospital with symptoms of progressive headaches of several months’ duration. Magnetic resonance imaging of the brain revealed a well-circumscribed, lobulated intraventricular mass with numerous intratumoral cystlike areas. The mass was located in the enlarged lateral ventricles bilaterally extending to the third and the fourth ventricle. Surgical removal of the 4th ventricle component of the tumor was performed. Histomorphological and immunohistochemical findings of the tumor were consistent with CN. After pathological diagnosis, gamma knife surgery was performed. CN may present with atypical features in a location with a usual histopathological findings. To our knowledge, we described the third case of tetraventricular CN, which was partially treated with both surgical resection and radiosurgery.

Central Neurocytoma Treated Using Supratentorial Ventricle Radiotherapy: A Single-Institution Analysis of Five Cases in Adjuvant or Salvage Settings After Surgery

“…Long-term follow-up and multiinstitutional studies may provide additional insights into the long-term efficacy and safety of adjuvant or salvage radiotherapy for CN. It should also be emphasized that CN can occur in the fourth ventricle, although rarely [22,23].…”

Central neurocytoma—positive and differential diagnosis: An example through a case report

“…10 At gadolinium injection, a degree of enhancement is seen. [11][12][13] In the largest MRI cohort driven by Li et al, 14 six characteristic features were validated to improve the diagnosis of CN, in which three new criteria were reported. The "scalloping sign," considered as a combination of ventricular wall undulations and spicules of peripheral cysts, was the most specific sign and is better depicted on sagittal views.…”