Tetrakis(triphenylphosphine)palladium(0)

Metal–Organic Frameworks with Zero and Low‐Valent Metal Nodes Connected by Tetratopic Phosphine Ligands

“…Stable complexes of zero‐valent metals are well‐known, and compounds such as tetrakis(triphenylphosphine)palladium(0) are widely used as pre‐catalysts in organic synthesis [9] . These low‐valent metal centers require soft Lewis base organic ligands that can act as π‐acceptors to form strong, coordinate covalent metal–ligand bonds [10] .…”

“…Stable complexes of zero-valent metals are well-known, and compounds such as tetrakis(triphenylphosphine)palladium(0) are widely used as pre-catalysts in organic synthesis. [9] These low-valent metal centers require soft Lewis base organic ligands that can act as π-acceptors to form strong, coordinate covalent metalligand bonds. [10] Using this guiding principle, Figueroa and co-workers recently reported the first example of a Ni 0 MOF using ditopic organic linkers with isocyanide metal-binding groups.…”

Functionalization of 1,3,4-Oxadiazoles and 1,2,4-Triazoles via Selective Zincation or Magnesiation Using 2,2,6,6-Tetramethylpiperidyl Bases

“… A mixture of Pd­(dba) 2 (3 mol %) and XantPhos (3 mol %) provided excellent results with a variety of electron-poor aryl iodides at 25 °C, producing the desired cross-coupling products 14a – 14e , 14h , and 14i in 73–98% yield. When employing electron-rich aryl iodides, Pd­(PPh 3 ) 4 (7.5 mol %) was the best catalyst and afforded the heterocycles 14f and 14g in 63–90% yield (50 °C, 2 h). Due to the relatively low reactivity of the intermediate organozinc species 13 , various functional groups were tolerated, including an ester ( 14b ), a chloride ( 14c ), a nitrile ( 14d ), an amine ( 14g ), and a nitro group ( 14h ).…”