2003
DOI: 10.1172/jci17786
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Tetrahydrobiopterin-dependent preservation of nitric oxide–mediated endothelial function in diabetes by targeted transgenic GTP–cyclohydrolase I overexpression

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Cited by 293 publications
(299 citation statements)
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“…We have previously shown that STZ-induced diabetes in C57BL/6 mice results in endothelial dysfunction [22]. To ensure that our findings were not specific to the C57BL/6 strain, we carried out similar experiments in Balb/c mice.…”
Section: Methodsmentioning
confidence: 98%
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“…We have previously shown that STZ-induced diabetes in C57BL/6 mice results in endothelial dysfunction [22]. To ensure that our findings were not specific to the C57BL/6 strain, we carried out similar experiments in Balb/c mice.…”
Section: Methodsmentioning
confidence: 98%
“…Animals and induction of diabetes by streptozotocin injection The mice used in this study were 12-to 14-weekold males and included the strains Balb/c (Harlan SpragueDawley, Bicester, UK), C57BL/6 (Harlan SpragueDawley) and GCH-Tg (specific overexpression of GTPCH in a C57BL/6 background, as previously described) as well as their wild-type littermates [22]. The experiments were conducted in accordance with the UK Home Office Animals (Scientific Procedures) Act of 1986.…”
Section: Methodsmentioning
confidence: 99%
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