Abstract:The tetracyclines are a group of antibiotics having an identical 4‐ring carbocyclic structure as a basic skeleton and differing from each other chemically only by substituent variation. The first tetracycline discovered was produced by a soil organism,
Streptomyces aureofaciens
, and is now known as chlorotetracycline. This compound ushered in a new era in antibacterial chemotherapy because it was effective orally and against a broad range of Gram‐positive and Gram‐negative bacteria. Th… Show more
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