Tetracaine hydrochloride 0.5% versus lidocaine 2% jelly as a topical anesthetic agent in cataract surgery

Abstract

TetraVisc was as effective as lidocaine 2% jelly as a topical anesthetic agent for routine cataract extraction.

Induction of apoptosis of rabbit corneal endothelial cells by preservative-free lidocaine hydrochloride 2%, ropivacaine 1%, or levobupivacaine 0.75%

“…[1][2][3][4][5][6] Lidocaine, ropivacaine, and levobupivacaine are 3 commonly used topical anesthetic agents in modern cataract surgery. [7][8][9] Topical anesthesia does not provide adequate motor and sensory anesthesia and may be associated with increased intraoperative pain and complications. 4 Therefore, intracameral injection of unpreserved lidocaine 1% has become a commonly used adjunctive anesthetic agent during cataract surgery.…”

The Effectiveness of 2% Lidocaine Gel Compared to 0.5% Tetracaine Eye Drop As Topical Anesthetic Agent for Phacoemulsification Surgery

“…However, this finding was inconsistent with other studies. Amiel et al, also found similar effectiveness between both anesthetic agents (4). Conversely, Chalam et al, found that the 0.5% tetracaine eye drop was more superior that the 2% lidocaine gel (5).…”

“…Amiel et al, mentioned that postoperative pain between 2% lidocaine gel and 0.5% tetracaine eye drop did not differ significantly (4). Chalam et al, mentioned the superiority of 0.5% tetracaine eye drop during intraoperative pain management in comparison with 2% lidocaine gel (5).…”

Lidocaine 2% jelly versus lidocaine 2%-sodium hyaluronate 0.3% drops in phacoemulsification surgery

“…This may imply a mild, temporary irritating effect of some constituents of the jelly, which has not been especially designed for the eye. Indeed, in the Product Monograph of a commonly used LJ (Xylocaine, AstraZeneca) [6], there is a clear warning to "avoid contact with eyes"; however, the use of LJ seems fairly established [1][2][3][4]. It should be stressed that the clinical significance of this effect on the conjunctiva remains rather elusive, as no major adverse general or eye-related outcomes became evident in our study.…”

“…Its advantages, such as the avoidance of repeated corneal irrigation [3], and its disadvantages, such as the difficulty in applying the appropriate amount of lidocaine jelly [4], have occasionally been discussed in the literature. Interestingly enough, the preparations of lidocaine per se may present differences with respect to their actions or side-effects [5].…”