TetR and OmpR family regulators in natural product biosynthesis and resistance
Rachit S. Patil,
Siddhant Sharma,
Aditya V. Bhaskarwar
et al.
Abstract:This article provides a comprehensive review and sequence‐structure analysis of transcription regulator (TR) families, TetR and OmpR/PhoB, involved in specialized secondary metabolite (SSM) biosynthesis and resistance. Transcription regulation is a fundamental process, playing a crucial role in orchestrating gene expression to confer a survival advantage in response to frequent environmental stress conditions. This process, coupled with signal sensing, enables bacteria to respond to a diverse range of intra an… Show more
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