Tetanus Toxoid Immunization Status and Associated Factors among Mothers in Hawzen, Eastern Zone of Tigray, Ethiopia, 2019

Mengesha, Meresa Berwo; Weldegeorges, Desta Abraha; Assefa, Natnael Etsay; Gebremeskel, Senait Gebreslasie; Hidru, Hagos Degefa; Teame, Hirut; Hailesilassie, Yared

doi:10.2174/1874944502013010281

“…Antenatal care follow-up during pregnancy was identified as a factor for tetanus toxoid immunization coverage among six primary studies included in this meta-analysis [ 30 , 36 , 40 , 42 – 44 ]. A total of 9,755 study participants were included to analyze the association between ANC visits and tetanus toxoid immunization.…”

Section: Resultsmentioning

confidence: 99%

“…The distance from home to the health facility was identified as a factor associated with receiving two or more doses of tetanus toxoid immunization among three primary studies with a total of 1,933 study participants [ 40 , 43 , 44 ]. Women who walk less than 1 hour to reach the health facility had 2.6 times higher to receive at least two doses of tetanus toxoid immunization than women who walk more than or equal to 1 hour to reach the health facility (OR = 2.64 (95% CI: 1.1, 6.6), I 2 = 94.1%) ( Table 4 , supplementary file three ).…”

Section: Resultsmentioning

confidence: 99%

Tetanus Toxoid Vaccination Coverage and Associated Factors among Childbearing Women in Ethiopia: A Systematic Review and Meta-Analysis

Nigussie

¹

,

Girma

²

,

Molla

³

et al. 2021

BioMed Research International

View full text Add to dashboard Cite

Background. Tetanus is a bacterial disease caused by the Clostridium tetani, which is a highly fatal, noncommunicable, and toxin-mediated disease. Globally, maternal and neonatal tetanus is a public health problem due to low maternal tetanus toxoid immunization. Ethiopia has the highest neonatal mortality and morbidity related to tetanus due to low tetanus toxoid immunization and the high number of home deliveries. The main objective of this systematic review and meta-analysis was to estimate the pooled coverage of at least two doses of tetanus toxoid immunization, and the pooled effect sizes of associated factors in Ethiopia. Methods. Primary studies for this review were searched from the PubMed/MEDLINE online, ScienceDirect, Hinari, Google, and Google Scholar databases. Primary articles published from 2010 up to August 30, 2020, were included in this meta-analysis. Data were extracted in Microsoft Excel format and exported to STATA Version 14.0. A random-effects meta-analysis model was used to estimate the pooled coverage of two or more tetanus toxoid immunizations and its associated factors. Heterogeneity was evaluated by the I 2 test. Egger’s weighted regression test was used to assess publication bias. Results. We retrieved 212 records; of these, 199 articles were excluded for reasons. Finally, 14 studies were included in this meta-analysis. The pooled estimate of receiving at least two doses of tetanus toxoid immunization coverage in Ethiopia was 52.2% (95% CI: 42.47-61.93, I 2 = 98.4 % ). Antenatal care ( OR = 7.8 (95% CI: 3.2, 19.2), I 2 = 96.3 % ), media exposure ( OR = 8.3 (95% CI: 2.1, 33.3), I 2 = 98.1 % ), distance from the health facility ( OR = 2.64 (95% CI: 1.1, 6.6), I 2 = 94.1 % ), educational status of women ( OR = 4.7 (95% CI: 2.07, 9.56), I 2 = 94.2 % ), and educational status of husbands ( OR = 2.995 (95% CI: 1.194, 7.512), I 2 = 92.5 % ) were factors significantly associated with receiving at least two doses of tetanus toxoid immunization coverage in Ethiopia. Conclusions. The coverage of tetanus toxoid immunization among childbearing women was low in Ethiopia. Strengthening maternal health service utilization (antinatal care and institutional delivery) to the nearest health facility even in health posts and empowering education for both women and their husbands is recommended to increase tetanus toxoid immunization coverage in Ethiopia.

show abstract

“…In this review, primary studies with a total of 13,731 study participants were included. The studies were conducted from 2010 to 2020 and were retrieved from ve regions of the country: 4 from the southern region, 3 from Amahara, 3 from Oromia, 1 from Tigray, 1 from Somalia, and another study was based on EDHS data [34][35][36][37][38][39][40][41][42][43][44][45][46]. All of these studies included in this review were community-based cross-sectional studies with sample sizes ranging from 239 to 7193 participants as reported from studies done in Bahir Dar and studies from EDHS data respectively [34,39].…”

Section: Characteristics Of the Included Articlesmentioning

confidence: 99%

“…Distance from home to health facility was identi ed as a factor associated with two or more tetanus toxoid immunization among three primary studies with a total of 1933 study participants [38,43,44]. Women who walked less than 1 hour to reach health facilities were 2.6 times more likely to take tetanus toxoid immunization than mothers who walked greater than or equal to 1 hour to reach the health facility [OR = 2.635 (95% CI; 1.1, 6.6)] (Figure 8).…”

Section: Meta-analysismentioning

confidence: 99%

Tetanus toxoid immunization Coverage and associated factors in Ethiopia: A systematic review and meta-analysis.

Nigussie

¹

,

Girma

²

,

Molla

³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Tetanus is a bacterial disease caused by the bacterium Clostridium tetanus which is a highly fatal, non-communicable, and toxin-mediated disease. Globally, both maternal and neonatal tetanus is a public health problem due to low maternal tetanus toxoid vaccination. The main strategies for the prevention of maternal and neonatal tetanus at birth were vaccination of the mothers with a protective dose of tetanus toxoid and clean delivery. Ethiopia has the highest neonatal mortality and morbidity related to tetanus in the world due to low tetanus toxoid immunization coverage and a higher number of home-deliveries. The main aim of this systematic review and meta-analysis was to estimate the pooled tetanus toxoid immunization coverage and associated factors in Ethiopia. Methods: The primary studies for this review were searched from PubMed/MEDLINE online, Science Direct, and Hinari databases. We retrieved 212 records; of these, 199 articles were excluded due to different reasons, and 13 studies were included in the systematic review and this meta-analysis. The data were extracted in Microsoft Excel format and exported to STATA Version 14.0 statistical software for analysis. Heterogeneity was evaluated by the I2 test. A random-effect meta-analysis model was used to estimate the pooled coverage of two or more tetanus toxoid immunization and its associated factors. Egger’s weighted regression and Begg’s rank correlation test were used to assess publication bias at a 5% significance level. Result: The pooled estimate of at least two dose of tetanus toxoid immunization coverage was 52.6% (95% CI 41.4%–63.8%). Ante-natal care (ANC) visits [OR = 7.8 (95% CI; 3.2, 19.2)], media exposure [OR = 8.3 (95% CI; 2.1. 33.3), distance from the health facility [OR = 2.635 (95% CI; 1.1, 6.6)], educational status of mothers [OR = 0.225 (95% CI; 0.105, 0.483) and husband educational status [OR = 0.184 (95% CI; 0.104, 0.323)] were significantly associated factors for tetanus toxoid immunization coverage in Ethiopia.Conclusion: The tetanus toxoid immunization coverage among childbearing women was low in Ethiopia. Strengthening maternal health service utilization (ANC, institutional delivery) to the nearest health facility including in health posts and empowering education is recommended to increase tetanus toxoid immunization coverage. Additionally, awareness creation on the advantage of taking tetanus toxoid immunization should be emphasized.

show abstract

“…The study done in western Ethiopia, Ilu Aba Bora, showed that only 310, or around 39.8%, of women were protected at birth against neonatal tetanus (20). The study conducted in Tigray, Ethiopia shows 40.2% of mothers were protected against neonatal tetanus during their last pregnancy (21) and a cross-sectional institutional study carried out in the University of Gondar comprehensive hospital revealed that 69.8% of mothers had received a protective dose of tetanus vaccine (22).…”

mentioning

confidence: 99%

Proportion of Births Protected Against Neonatal Tetanus and Its Associated Factors Among Mothers Who Gave Birth Within the Past 6 Months in Gozamn District, Northwest Ethiopia, 2022

Gashaw

¹

2022

Preprint

0

View full text Add to dashboard Cite

Introduction: An estimated 3.3 million newborn deaths occur each year around the world, with 9,000 babies dying every day in their first 28 days. Neonatal tetanus is tetanus that occurs within the first 28 days of life, and maternal immunization can reduce neonatal tetanus by 94%. However, not enough mothers were vaccinated to protect against neonatal tetanus globally, and only 49% of mothers in Ethiopia were protected. The proportion of mothers who were protected from neonatal tetanus was not determined yet in the study area. Because neonatal tetanus is such a serious disorder with such a high fatality rate and there is a need for more recent evidence on it, more research on birth protection against neonatal tetanus is needed. Objective To assess the proportion of births protected against neonatal tetanus and its associated factors among mothers who gave birth within the past 6 months in Gozamn district, Northwest Ethiopia, 2022. Method A community-based cross-sectional study was conducted in the Gozamn district, Northwest Ethiopia from April 1–30, 2022. A total sample size of 831 was used, and a two-stage stratified sampling technique was used. A structured and pre-tested questionnaire was used to collect the data, and the data was analysed by using StataV14. A logistic regression analysis was conducted, and the level of statistical significance was determined by a p-value of less than 0.05. Result The proportions of birth protected against neonatal tetanus were 58.57% in the study. Mother who had radio (AOR = 3.09,95%CI: 2.09, 4.56), mother who travel less than one hour to reach nearest health facility (AOR = 1.96,95%CI: 1.23,3.10), mother who gave birth of their last child in the health institution (AOR = 4.17,95%CI:2.39,7.28), mothers who had information from health professional (AOR = 2.56,95%CI:1.56,4.19) and > 4 ANC visit (AOR = 2.57,95%CI:1.55,4.26) were positive predictors of birth protected against neonatal tetanus. Conclusion In this study area, the proportion of mothers protected against neonatal tetanus was low. Professional based counselling related to TT vaccine, as well as interlinks and strength of different health care services such as ANC and delivery services are vital to increase proportion of birth protected against neonatal tetanus.

show abstract

Tetanus Toxoid Immunization Status and Associated Factors among Mothers in Hawzen, Eastern Zone of Tigray, Ethiopia, 2019

Cited by 12 publications

References 6 publications

Tetanus Toxoid Vaccination Coverage and Associated Factors among Childbearing Women in Ethiopia: A Systematic Review and Meta-Analysis

Tetanus Toxoid Vaccination Coverage and Associated Factors among Childbearing Women in Ethiopia: A Systematic Review and Meta-Analysis

Tetanus toxoid immunization Coverage and associated factors in Ethiopia: A systematic review and meta-analysis.

Proportion of Births Protected Against Neonatal Tetanus and Its Associated Factors Among Mothers Who Gave Birth Within the Past 6 Months in Gozamn District, Northwest Ethiopia, 2022

Contact Info

Product

Resources

About