Tetanus Successfully Treated with Gallamine Triethiodide

Smith, Eric; Thorne, Napier

doi:10.1136/bmj.2.4797.1291

Cited by 6 publications

(1 citation statement)

References 4 publications

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“…Agents without continuous artificial respiration. It is certainly possible to control convulsions without depressing respiration sufficiently to require artificial respiration, 51, 82,94,170,195,265,271,272,296,298,310,332,343,381 but it is difficult, 15,154,198,238,268,319,360,364,378,399 and patients cannot generally be safely left alone, for artificial respiration is liable to be needed from time to time. Because of the relative ease of reversing the effect of drugs acting by competition, they would seem to be preferable to depolariZing neuromuscular blocking agents.…”

Section: Neuromuscular Blocking Agentsmentioning

confidence: 99%

Pathologic physiology, pharmacology, and therapeutics of tetanus

Laurence

Webster

1963

Clin Pharma and Therapeutics

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Experimental evidence for the routes of tramport of tetanus toxin from the site of its formation to the central nervous system is reviewed. The possible sites and mechanisms of action of toxin are discussed, and an attempt is made to correlate the mode of action with that of drugs used to suppress convulsions. Despite the total absence until recently of any valid therapeutic comparisom, an attempt is made to evaluate the principal controversial therapeutic techniques, including antitoxin, care of the wound, chemotherapy, central anticonvulsants, neuromuscular blocking agents, tracheostomy, and adrenocortical steroids.

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