Tests of the Responsiveness of the COPD Assessment Test Following Acute Exacerbation and Pulmonary Rehabilitation

The Development and Validation of a New Questionnaire to Address the Gap between the Actual and Desired States in COPD Patients

“…These two measures have been emphasized in the symptom assessment of COPD patients following the revision of GOLD 2011 [3]. It has been reported that CAT can appropriately evaluate disease worsening [20] and progress in rehabilitation [21]. A close correlation between the mMRC dyspnea scale score and prognosis has also been reported [22].…”

Clinical Application of the COPD Assessment Test

“…The 2013 update to the GOLD strategy includes the use of the CAT to evaluate symptoms, defining a score ≥10 as health impairment and including them in GOLD grades B and D (2). CAT is an easy to use, validated, and reproducible tool that allows disease severity to be categorized (4) and is sensitive to health status changes during exacerbation and following pulmonary rehabilitation (PR) (5). The CAT behaves the same way across different European countries (4).…”

“…This information indicates the consistency of CAT measurements at one year. Based on the previous data published on CAT score variations during COPD exacerbation (5,6,14), we arbitrary designated ±4 points as a significant longitudinal variation in the CAT score. We acknowledge the potential limitations of this cut-off value, but due to the limited information available on longitudinal changes in CAT scores, we decided to use the available data to select a In patients in whom the CAT scores changed, the changes were significantly associated with only MMRC dyspnea.…”

“…CAT scores correlate well with other specific heath-related quality of life indicators in COPD patients (4), capturing the effect of different treatments, such as those included in COPD exacerbation or pulmonary rehabilitation (5,6). CAT scores have been associated with important representative parameters of the disease (5), such as lung function, dyspnea, exercise capacity, and exacerbation in the previous year, and behave well across different European countries (4). However, little is known about its longitudinal behavior.…”

“…, Cristina Martinez-Gonzalez MD 3 , Pilar de Lucas-Ramos MD 4 , Isabel Mir-Viladrich MD 5 , Borja Cosio MD 6,23 , German PecesBarba MD 7,23 , Miryam Calle- Rubio MD 8 , Ingrid Solanes-García MD 9 , Ramón Agüero Balbin MD 10 , Alfredo de Diego-Damia MD 11 , Nuria Feu-Collado MD 12 , Inmaculada Alfageme Michavila MD 13 , Rosa Irigaray MD 14 , Eva Balcells MD 15,23 , Antònia Llunell Casanovas MD 16 , Juan Bautista Galdiz Iturri MD 17,23 , Margarita Marín Royo MD …”