Tests for so-called capillary fragility of the skin and the significance of positive tests in vascular disease

Thrombocytopenia and Leucopenia Following Carbutamide

“…Comparatively little attention has been paid to this aspect.of diabetic vascular disease, but it is of obvious importance in the investigation of thrombocytopenia ind bleeding disorders in such patients. Several papers deal with the subject, notably those of Beaser et al (1944), Rodriguez and Root (1948), Barnes (1950), and Hines et al (1953). There is general agreement that positive tests are common and that the incidence is related to the duration of the diabetes rather than to its severity or to the age of the patient.…”

Premature Vascular Degeneration in Diabetes Mellitus: Pathogenesis, and Relation to Aging

“…In “insulin‐deficient” diabetes there seems to be evidence of a similar weakness of blood vessels (11), namely: 1) hemorrhages in the fundi, 2) capillary aneurysms in the fundi, and 3) increased capillary fragility (12–15).…”